Pumping fluid is one of the crucial parts of any microfluidic system. Using electric and magnetic fields as a substitute for moving parts can have many advantages. In this study hydrodynamic and heat transfer characteristics of electroosmotic flow under influence of lateral electric and transverse magnetic field, are studied numerically. Results indicate that the dimensionless parameters such as Hartmann number, intensity of the lateral electric field, pressure gradient parameter and aspect ratio have an important role in controlling flow. It can be implied that the enhancement of pressure gradient leads to the decrease of critical Hartmann number, and this dependency can be reduced from 44% to 7% for S=0.5 to S=50 in two pressure gradients of Ω=1 and Ω=20. In addition, the reduction of aspect ratio of microchannel section leads to the increment of critical Hartmann number in a specified lateral electric field. At the end, thermal analysis is being done by consideration of the effects of magnetic and electric fields on the Nusselt number.
Urolithiasis is a common worldwide problem with high recurrence. This review covers Euphorbiaceae twenty (20), Cucurbitaceae eighteen (18), Acanthaceae and Amaranthaceae fifteen (15), Cupressaceae twelve (12), Caryophyllaceae eleven (11), Anacardiaceae ten (10), Amaryllidaceae, Apocynaceae and Asparagaceae nine (09), Ericaceae and Equisetaceae eight (08), Arecaceae and Caesalpiniaceae seven (07), Chenopodiaceae six (06), Aspleniaceae, Capparidaceae and Crassulaceae five (05) plants used globally in different countries. Hopefully, this review will not only be useful for the general public but also attract the scientific world for antiurolithiatic drug discovery.
The use of nanotechnology in healthcare and medicine is crucial, particularly for nanocoatings. The therapeutic potential of nanocoatings on medical implants and devices is examined in this chapter. It goes into the ingredients, production processes, and health benefits of nanocoatings. Device functionality and biocompatibility can be enhanced by nanocoatings. They are essential in addressing healthcare issues including cardiovascular stents and orthopedic implants. Additionally, nanocoatings are used in medication delivery systems, tissue engineering, and wound healing. This chapter offers important knowledge on the medical applications of nanocoatings to experts and researchers. Nanotechnology has the potential to alter the medical industry, which would be advantageous for patients.
Neuroblastoma is the most prevalent extracranial solid tumor in pediatric patients, originating from sympathetic nervous system cells. Metastasis can be observed in approximately 70% of individuals after diagnosis, and the prognosis is poor. The current care methods used, which include surgical removal as well as radio and chemotherapy, are largely unsuccessful, with high mortality and relapse rates. Therefore, attempts have been made to incorporate natural compounds as new alternative treatments. Marine cyanobacteria are a vital source of physiologically active metabolites, which have recently received attention owing to their anticancer potential. This review addresses cyanobacterial peptides' anticancer efficacy against neuroblastoma. Numerous prospective studies have been carried out with marine peptides for pharmaceutical development, including research on anticancer potential. Marine peptides possess several advantages over proteins or antibodies, including small size, simple manufacturing, cell membrane crossing capabilities, minimal drug-drug interactions, minimal changes in blood-brain barrier (BBB) integrity, selective targeting, chemical and biological diversities, and effects on liver and kidney functions. We discussed the significance of cyanobacterial peptides in generating cytotoxic effects and their potential to prevent cancer cell proliferation via apoptosis, the activation of caspases, cell cycle arrest, sodium channel blocking, autophagy, and anti-metastasis behavior.
Background: Allied health science students often experience elevated academic stress due to the demanding nature of their curricula, which blend theoretical instruction with clinical practice. Examination periods, in particular, exacerbate psychological pressure, potentially compromising academic performance and overall well-being. Physical activity (PA) has been widely recognized for its protective role against stress, yet limited research has been conducted specifically among allied health science students. This study examined the correlation between physical activity and perceived stress levels among undergraduate allied health students during examination periods at Desh Bhagat University. Methods: A descriptive cross-sectional correlational study was conducted over eight weeks, from October to November 2024. 250 undergraduate students were proportionately and randomly selected from the Nursing, Physiotherapy, Radiography, and Medical Laboratory Science departments. Data collection instruments included the International Physical Activity Questionnaire–Short Form (IPAQ-SF) and the Perceived Stress Scale (PSS-10). Descriptive statistics, Pearson’s correlation, and one-way ANOVA were performed using SPSS version 25 to analyze the data. Results: Out of 250 questionnaires distributed, 237 were deemed valid for analysis. Among the respondents, 40.9% reported low physical activity, 38.4% moderate, and 20.7% high. In terms of stress levels, 65.4% experienced moderate stress, and 19.4% reported high stress. A statistically significant negative correlation was observed between physical activity and perceived stress (r = -0.42, p < 0.001). Furthermore, one-way ANOVA revealed that students with higher physical activity levels had significantly lower stress scores (F = 18.93, p < 0.001). Conclusion: Physical activity is an effective non-pharmacological strategy for mitigating academic stress among allied health science students. The results highlight the importance of promoting regular physical activity, particularly during high-stress academic periods, as a means of enhancing mental well-being and academic success.
The contribution of financial perspective measures to improving organizational performance is empirically examined in this article. The study examines how financial metrics like ROI, cost control, profitability, and revenue growth relate to organizational effectiveness using the case of MTN Ghana. It is based on the balanced scorecard framework. The study uses a quantitative approach to investigate the relationship between financial performance metrics and important success indicators like market share, operational effectiveness, and shareholder value, using data from a dataset of different companies in multiple industries. The results of the study show how important financial perspective metrics are for reaching competitive advantage and sustainable growth. Businesses that put a high priority on strategic fiscal management typically perform better, especially when it comes to cost-effectiveness, liquidity, and profit margins. But the study also highlights the drawbacks of depending only on financial indicators. To create a more thorough performance evaluation system, it emphasizes the need to combine financial measurements with non-financial indicators like employee development, internal processes, and customer satisfaction. In summary, the study offers practitioners and scholars useful information by offering evidence-based recommendations for enhancing financial strategies. Organizations can develop a balanced approach to performance measurement that promotes long-term success by using both financial and non-financial metrics. The article ends with practical suggestions for businesses looking to increase output and streamline their budgets.
Turcicum leaf blight (TLB) and Polysora rust diseases are taking heavy shiver in all maize growing regions of Karnataka. Several new fungicides are used to control the diseases, among them strobilurin group fungicides in combination with triazolefungicides are found effective in management of diseases. A mixture of Trifloxystrobin 50 WG + Tebuconazole 250 EC and mixture of Azoxystrobin 25 SC + Difenoconazole 25 EC were used in this study to manage the TLB and Polysora rust. The two combination fungicides were evaluated in different days against TLB and Polysora rust on two susceptible varieties namely 219J and CM 202. Results revealed that mixture of Trifloxystrobin 50 WG + Tebuconazole 250 EC @ 0.7 g/lit and mixture of Azoxystrobin 25 SC + Difenoconazole 25 EC @ 2.5 ml/litwere found effective in the management of TLB (15.0 % and 11.0 % respectively) and mixture of Trifloxystrobin 50 WG + Tebuconazole 250 EC @ 0.7 g/lit were found effective in controlling Polysora rust (13.2 %). Allied to yield, more significant increase in yield was recorded in treatment Trifloxystrobin 50 WG + Tebuconazole 250 EC @ 0.7 g/lit (5131.1kgs/ha). While, mixtures of Azoxystrobin 25 SC + Difenoconazole 25 EC @ 2.5 ml/lit recorded yield of 5913.0 kgs/ha, this was significantly superior with respect to disease control and yield aspects.
The purpose of this study was to find out the effects of yoga practices on selected physiological parameters of Bharathidasan University inter-collegiate men Football players. The study was conducted on thirty Football players from various colleges who have participated in Bharathidasan University Tiruchirappalli, Thanjavur Divisional tournaments 2019-2020. Subjects were randomly assigned equally into two groups, Group –I underwent yogic practices group (n=15) and group II (n=15) acted as control group. Resting pulse rate, Breath holding time and Cardio respiratory endurance were selected as creation variables. The training programme was restricted to 12 weeks and the number of session was 3 days per week. Resting pulse rate was assessed by Radial pulse method, Breath holding time was assessed by Manuel method and Cardio Respiratory Endurance was assessed by Cooper’s 12 minutes run/walk test. The data was collected from the experimental and Control Groups before and after the 8 weeks of training programme were statically examined with Analysis of covariance (ANCOVA). Resting Pulse Rate, Breath Holding Time and Cardio Respiratory Endurance showed significant difference between the groups.
Plants have been used as medicine for the treatment of diseases for thousands of years. These herbal remedies, although natural, can cause some serious damaging effects on the vital organs of the body due to inadequacy in standardization and safety regulations. Mucuna pruriens Linn. belongs to the family Fabaceae and is used traditionally in various ailments. The present study reports the acute systematic toxicity and topical toxicity of methanolic extract of Mucuna pruriens (seeds) on albino mice and rabbits respectively. The test solution was injected intravenously into the tail as 1ml/20gm of the mice body weight. The observation was made immediately and after 1/2, 1, 4, 24, 48 and 72hours of drug administration. Mice showed normal activity till 72hours. The intracutaneous test is designed to evaluate local responses to the extracts of materials under test following intracutaneous injection into rabbits. The toxicological investigations of Mucuna pruriens with particular reference to intracutaneous toxicity in experimental animals displayed that it showed slight edema.
Cardiovascular diseases represent a formidable global health challenge, standing as the foremost cause of both mortality and morbidity. Atherosclerosis and myocardial infarction, as primary contributors to this epidemiological burden, underscore the urgent need for effective therapeutic interventions with minimal side effects. Natural compounds derived from plants have emerged as promising candidates, given their enhanced efficacy and reduced adverse effects. Phytochemicals, in particular, have garnered attention for their potential as alternative therapeutic agents. This review delves into the cardioprotective potential of pinocembrin (5,7-Dihydroxy flavanone), a compound extracted from various plants and honey. Renowned for its antioxidant and anti-inflammatory properties, pinocembrin demonstrates significant cardioprotective effects through the modulation of diverse signaling pathways. Atherosclerosis and myocardial infarction entail intricate cellular mechanisms involving oxidative stress, inflammatory responses, cellular remodeling, and programmed cell death. Pinocembrin, by targeting key factors within these pathways, exhibits cardioprotective actions. While existing research underscores its effectiveness, further investigations are warranted to elucidate the impact of pinocembrin on additional cardiovascular conditions and explore novel molecular targets, thus paving the way for future advancements in therapeutic interventions.
Purpose: With an increase in updated technologies use of Fintech services have also been increased. Intention to use of Fintech services largely depend upon attitude of individuals towards adoption of these services. Drawing upon the Technology Innovation Model (TAM) theory this paper observes different factors associated with customer’s attitude towards acceptance of fintech facilities provided by banks that in turn affect intent about usage of these services. The features like Supposed Utility, Apparent Comfort for Usage, Supposed Peril, Trust Factor, Administration Sustenance, Consumer Innovativeness, Attitudes in the direction of Acceptance, Intent in the direction of Adoption are used in this study. Methodology: The data was collected from residents of Delhi using a survey method through online mode. A well-structured questionnaire was circulated among customers with the help of employees of each branch by using the online platform WeChat. Also, Questionnaire was circulated among customers with the help of employees of each branch who gave them proper instructions to fill the questionnaire. It was circulated through WeChat. To inspect the strength of the association amid factors, , Confirmatory Factory Analysis (CFA) and regression path analysis were applied using SEM in AMOS software. Findings: The findings revealed that Government Support is a key predictive variable for the adoption of Fintech services. Whereas Perceived Ease of Use and Perceived Risk are not significantly supported the attitude towards adoption of Fintech services. While other factors slightly supported attitude towards adoption. Practical Implications: The findings of this article are useful for banks to provide empirical framework for customers to adopt new, user-centered fintech services. Originality/Value: This article in useful for the banking institutions, Government agencies and insurance companies provide empirical framework for customers to adopt new, user-centered fintech services.
Arisaema jacquemontii Blume (Araceae) is a medicinally important plant for treating different diseases, especially dermatological disorders. Alkaloids, phenols, terpenes, flavonoids, glycosides, and tannins have been reported from this plant. Antioxidant, antifungal, antibacterial and anticancer activities are also shown by Arisaema jacquemontii. The present review attempts to compile all the previous data based on its medicinal uses, phytochemistry and pharmacology reported in the earlier articles.
The global endeavor to develop and deploy COVID-19 vaccines has underscored both significant scientific progress and enduring disparities in worldwide access. This analysis examines regional vaccine distribution patterns across World Health Organization (WHO) regions—Africa, the Americas, Eastern Mediterranean, Europe, and Western Pacific—revealing substantial variations in vaccine types and manufacturer contributions. Data indicate that the Americas and Europe demonstrate a broad vaccine portfolio, with prominent contributions from major international pharmaceutical companies alongside regionally developed vaccines. Conversely, African, Eastern Mediterranean, and Western Pacific regions show considerable reliance on vaccines from Asian (notably China and India) and Russian manufacturers, in addition to Western products. This distribution highlights the influence of geographical proximity to manufacturing centers, regional alliances, and local production capabilities (e.g., CIGB and Finlay in the Americas, COVIran Barakat in the Eastern Mediterranean, and various Chinese products in the Western Pacific) on vaccine availability. Predominant vaccines by country count include Pfizer-BioNTech's Comirnaty, AstraZeneca's Vaxzevria, Janssen's Ad26.COV2-S, Moderna's Spikevax, Beijing CNBG's BBIBP-CorV, and SII's Covishield. The observed regional variations in vaccine types and supply chains carry implications for comparative effectiveness research, the understanding of differential immune responses, and the evaluation of pandemic control strategies. Furthermore, inconsistencies in global data reporting and product nomenclature present challenges for comprehensive analysis. The findings emphasize the importance of diversified supply chains, the growing role of regional manufacturing in enhancing global health security, and the need for standardized global data for a more profound understanding of vaccine equity and efficacy to inform future pandemic responses.
Purpose – The purpose of this review is to critically analyse the extant research and help readers understand the ways the school-based comprehensive sexuality education (CSE) can contribute towards youth development and urge policymakers to implement nationwide good-quality, scientific, culturally relevant, age-appropriate and holistic school-based CSE. Design/methodology/approach – This literature review has been designed using the extant information available on Google Scholar, Web of Science (WoS) and PubMed. Findings – The findings of this review inform that there is a significant need amongst the youth of the day for good-quality, scientific, culturally relevant, age-appropriate and holistic school-based CSE. Also, the findings suggest that there are significant associations between school-based CSE and youth development. Research limitations/implications – This research paper although draws from extant literature about sexuality education and its delivery across the globe, it applies the sexuality education scenario in India. Practical implications – The findings of this review aim to implicate nationwide policy-level changes to implement CSE in the school curricula. There are more practical behavioural changes that CSE could foster amongst students, which are discussed in the review. Social implications – Due to the behavioural changes that CSE could foster amongst students, it may help in the upbringing of responsible citizens who are free of health complications, who can make independent health related decisions and look after each other in the community. Originality/value – This review is an original contribution from the author. Whilst there is extant literature about CSE and youth development, this article fills the void by investigating the interdependent contributions that both the concepts can make to one another and encourages more research on this topic.
The free senior high school policy is one of the best social and economic intervention policies that openly affect both parents and their wards in senior high school. This realisation is reached on the backdrop of the policy’s role in redeeming parents from their economic and financial burden. This study, therefore, looks at the effect of introducing the free senior high school policy on the economic and social lives of parents and students respectively. A correlational cross-sectional descriptive design was used. Questionnaires were administered to three hundred and thirty-six (336) parents of wards in three senior high schools in the North East and Upper East Regions of Ghana. The study confirms that the introduction of the free senior high school policy relieved the financial burden of parents, especially guardians from rural settlements. Besides, there was a lack of adequate stakeholder consultation, hence saddled with implementation challenges. Delay in disbursement of funds for feeding and learning materials presented yet another problem. It is important that governments find sustainable sources of funding for the educational system and also ensure the double-track system is regularised into a single-track system by expanding academic user facilities and increasing the numerical strength of both teaching and non-teaching staff in various senior high schools.
Over the years, pharmacy has developed from a simple floor stock system to a complex unit dose, I.V. additive, and clinical pharmacy program. This development would have never been possible without the support of the nursing, medical, and administrative staff. The support of obtained slowly by developing services that increase the pharmacist's credibility as a team member concerned with the pediatric and neonate patients. These services include a unit dose program, I.V. additive program, drug information services, and pharmacy medication program. One area in which pharmacist does not obtain a background from generalized training is the area of pediatric dosing. Pediatric pharmacists must learn in clinical practice the proper dosing of the pediatric patient and neonate patient. The dose must be checked periodically. In the premature or newborn infant, the pharmacist must consider the immature renal and hepatic function so that he/she does not overdose initially and then underdose as the infant grows and matures. Neonates are a special group of children, they are less than 30 days, and within this group preterm babies (that means less than 37 weeks). Determining the correct dose for drugs used to treat neonates is a critically vital factor. Prematurity affects kidney and liver function and the proper adjustment of drug doses is crucial [1]. The absence of drug level necessitates the adjustment of drug doses and the presence of qualified oriented dependable pharmacists. Drug doses are not numbers, or decimals used within the therapeutic range. Neonatal Intensive Care Unit (NICU) needs a system for the calculation and preparation of drugs [2].
Mediterranean journal of pharmacy and pharmaceutical sciences
Corporate social responsibility is a self-equipped business approach that helps an organization be socially responsible to its stakeholders and the overall public. Through the practice of CSR, companies are conscious and aware of the impacts they have on all aspects of society, including economic, social, and environmental (Goel and Ramanathan, 2014, p. 51). A case study scenario, in this case, is of StanBed Tours Ky, the impact of CSR on consumer loyalty, stating that the increase of CSR has resulted in the society's satisfaction with the business (Bediako, 2017, p. 1). CSR influences the people affected by it in various intensities and means. Such as, employees, who are part of the major stakeholders, are significantly affected by the organization's corporate social responsibility activities in marketing, which shape their logic, inspiration and lead to deeper commitments to achieving organizational goals and strategic plans (Makasi et al., 2014, p. 2600). Additionally, CSR investments in marketing significantly impact external shareholders such as consumers and the organization's image (Kaman, 2015, p. 7). CSR activities carried out by StanBed include tree planting exercises to mitigate carbon dioxide emissions resulting from flying airplanes, voluntary beach cleaning services to protect marine life, and providing educational services to children in the community of tours.
The evolution in Information Technology has gone a long way of bringing Igbo, one of the major Nigerian languages evolved. Some online service providers report news, publish articles and search with this language. The advancement will likely result to generation of huge textual data in the language, that needs to be organized, managed and classified efficiently for easy information access, extraction and retrieval by the end users. This work presents an enhanced model for Igbo text classification. The classification was based on N-gram and K-Nearest Neighbour techniques. Considering the peculiarities in Igbo language, N-gram model was adopted for the text representation. The text was represented with Unigram, Bigram and Trigram techniques. The classification of the represented text was done using the K-Nearest Neighbour technique. The model is implemented with the Python programming language together with the tools from Natural Language Toolkit (NLTK). The evaluation of the Igbo text classification system performance was done by calculating the recall, precision and F1-measure on N-gram represented text. The result shows text classification on bigram represented Igbo text has highest degree of exactness (precision); trigram has the lowest level of precision and result obtained with the three N-gram techniques has the same level of completeness (recall). Bigram text representation technique is extremely recommended for any text-based system in Igbo. This model can be adopted in text analysis, text mining, information retrieval, natural language processing and any intelligent text-based system in the language.
Concrete is a material which is used in construction. Weight of concrete plays a major role in the construction industry. If the weight of the concrete is increased, it will pose more structural problems on the later date of construction. It also increases the cost of construction, without any specific benefit. So if lightweight concrete is used, it not only reduces cost of construction, but also not poses any structural problems unnecessarily. Light weight concrete also aids workers in smooth handling of materials. In this study, vermiculite in the form of exfoliated form is used to replace partially natural sand. By this action dead weight of the structure is reduced. Once the dead weight of structure is reduced, it in turn reduces cost of construction. In this study three mixes were casted with the cement content of 383 kg/m3 in M20 concrete and the water cement ratio of 0.45 is chosen. Vermiculite at 10%, 20% and 30% are choosing to partially replace the natural sand. The Tests conducted on concrete for evaluating mechanical properties include compressive strength and split tensile strength. For evaluating durability properties, tests like acid resistance, sulphate resistance, chlorine penetration and water absorption.
A Novel route one-pot three-component reaction was developed for the synthesis of 2,3-Dihydro-2-phenyl-1- H-Naphtho-[1,2-e] [1,3] Oxazine by using Substituted Aniline, Formalin & β-Naphthol in the presence of Tannic acid (10 Mol %) as catalyst. The reaction is observed by using TLC, after completion of reaction product is characterized by 1H, NMR, 13C NMR, IR and Mass Spectra.