A zoonotic disease is an infectious disease caused by pathogens such as bacteria, virus, rickettsia, fungi, parasite or prion that has been transmitted from an animal, especially a vertebrate to human beings. Usually, the first infected human transmits the infectious agent to other humans very rapidly; it is one of the important concerns of zoonoses. The World Health Organization (WHO) currently list the Emerging infectious diseases (EID) of epidemic issues in their research and development blueprint as COVID-19 (Corona viruses), Middle East Respiratory Syndrome (MERS), Severe Acute Respiratory Syndrome (SARS), Ebola and Marburg viruses (Filovirus), Crimean Congo haemorrhagic fever (Nairo virus), Lassa Fever (Lassa virus), Nipah (Henipa virus ), Rift Valley fever (Phlebo virus) and Zika (Flavi virus). Due to the deadly pandemics facing by the globe, it is essential to understand the way of transmission of emerging viruses, its mode of infection and important measures to eliminate or control them from the world is essential. However, mankind overcomes so many deadly viruses with the help of scientific knowledge, through vaccination, new therapies, drugs etc. Nowadays, viral zoonoses like rabies (Lyssa virus) are 100% preventable through vaccination and medication even though, humans face lots of new threats especially emerging zoonosis diseases like Covid19. This review summarized the major zoonotic viruses affecting human beings, their source, pathogenicity and its important ways to overcome the transmission of microbes from animal to humankind.

Dr. saranya devi k

In this article, we form the exact wave solutions of the Jimbo-Miwa equation and the Calogero-Bogoyavlenskii-Schiff equation by applying the new generalized (G'/G)-expansion method. We explained the new generalized (G'/G)-expansion method to look for more general traveling wave solutions of the above mentioned equations. The traveling wave solutions attained by this method are in terms of hyperbolic, trigonometric and rational functions. The graphical representation of the obtained solutions is kink soliton, singular kink soliton, singular soliton and singular periodic solution. This method is very significant for extracting exact solutions of NLEEs which habitually occur in mathematical physics, engineering sciences and applied mathematics.

Md khorshed alam

Zn1-xCdxO (x=0, 0.04, 0.06, 0.08) ternary alloys were successfully synthesized by Sol–gel method. The prepared powders were sintered at 800°C for 4hrs. The compositional, structural and optical studies were investigated by SEM equipped with EDS, XRD and UV-Visible Spectroscopy. XRD results were compared with JCPDS data and confirmed the formation of Cd doped ZnO nanoparticles with polycrystalline single phase hexagonal wurtzite structure. The crystallite size was found to decrease from 21 to 17 nm with increase in the concentration of Cd. EDS analysis revealed the existence of Cd content in ternary alloys. From Ultraviolet-visible spectral studies optical band gap vary from 3.21 eV to 3.12 eV with Cd concentration. © 2016 Elsevier Ltd. All rights reserved. Selection and Peer-review under responsibility of International conference on materials research and applications-2016.

Mohan kumar thumma komma

formulation and evaluation of herbal face pace pack

Sumaira taj

India holds a crucial place in the worldwide leadership of sustainable development since it is the largest democracy in the world and has one of the nations with the greatest economic growth. With innovation, inclusivity, and sustainability at its core, Viksit Bharat @2047 symbolizes India's ambition to become a fully developed country by the century of its independence. Emerging technologies are increasing productivity, boosting global competitiveness, and spurring innovation in various industries. By providing tailored financial assistance & investment suggestions, artificial intelligence-powered chatbots & robo-advisors are democratizing the provision of financial planning services. Decentralized finance (DeFi) systems and other blockchain-based solutions are simplifying trade finance procedures, lowering operating costs, and facilitating safe and transparent cross-border transactions. This chapter examines how innovation and technology are essential to achieving this lofty goal. It provides a thorough examination of India's contemporary digital infrastructure, the country's ascent in international innovation rankings, & the use of cutting-edge technologies including biotechnology, renewable energy, artificial intelligence, and space research. The story highlights government programs such as Start-up India, Digital India, and the National AI & Green Hydrogen Missions. Furthermore, the story underscores the importance of inclusive growth, which encompasses youth empowerment, women-led innovation, and rural digitization. Alongside strategic advice, issues like cybersecurity concerns, low investment in research and growth, and the digital divide are also discussed. India is positioned to emerge as a worldwide leader in technology, not simply a consumer, by cultivating a strong innovation ecosystem and utilizing partnerships between university, industry, and the private sector. This chapter provides a comprehensive plan for a tech-powered, inclusive, and sustainable Viksit Bharat before 2047. Higher education is one of the areas that must use developing technology, especially artificial intelligence (AI), to achieve Viksit Bharat 2047 (the Developed India 2047). Outside of higher education, artificial intelligence influences technology and economic progress. Young minds will realize this transformative vision as soon as they actively interact with AI. AI literacy empowers students in higher education to investigate, produce, and innovate. Students may do research, find solutions to real-world issues, and alter the course of history as they learn AI.

Dr. awadhesh singh gautam

The screening of perfect diuretics for non-clinical utility in Diabetes mellitus is a relatively novel approach which gain inssight into underlying the pathophysiological processes. This study is aims to evaluate the diuretic effect of a crude aqueous & alcoholic extract of M.charantia Linn. using Albino Wistar Rat model. In this study, the comparative observation of Diuretic activity with standard and extracted compound were shown that the estimated 24‐hour urine contains the Na+ - 3.82 g, 3.82 g, 3.92 g and K+ - 1.35 g, 1.39 g, 1.48 g wt. for Vehicle control, Standard drug, and Extracted compound respectively. Which possess the favoring result means from the spot urine were 10.7±7.0 g/24 h and 3.9±2.1 g/24 h, respectively. Coefficients were 0.035, 0.022, 0.046 at (d±2SD = 7.07 g, 4.42 g and 8.92 g) for sodium chloride and 0.068, 0.031, 0.046 at (d±2SD =4.92 g, 2.31 g, and 3.34 g) for potassium chloride. The Na+ and K+ results can be deduced by conversion (1 g NaCl=0.4 g Na+, 1 g KCl≈0.5 g K+). The present study guide formulation of non clinical trials with statistical study to further measuring the claimed efficacy of M. charantia as a natural remedy for diabetes mellitus.

Wahul umesh

Nature provides drugs in the form of medicinal plants to cure all ailments of mankind with fewer side effects. These medicinal plants can cause some serious damaging effects on the vital organs of the body too; there is a need of toxicity studies to provide their safe use both in human and animals. The present study reports the acute systemic toxicity of methanolic extracts of leaves of Adenanthera pavonina L., Peltophorum roxburghii Deneger., Prosopis cineraria Druce and Prosopis juliflora DC., (Mimosaceae) in swiss albino mice to explore their suitable doses for pharmacological screening. Observations were made immediately and after 1/2, 1, 4, 24 and 48hours of intraperitoneal drug administration. Adenanthera pavonina extract at the dose of 150 mg/kg body weight is considered to be safe. Whereas remaining extracts of investigated plants are relatively safe at the dose of 100 mg/kg body weight.

Dr. salman ahmed

International students are the bedrocks of the global higher education market. Thus, worldwide, higher education institutions (HEIs) focus most international marketing efforts on understanding the complexities surrounding this student market. Recent studies on international higher education reveal the choices made by this student cohort and a wide variety of factors influencing such selections. This present study focuses on a student decision that is made under a set of options. Using structural equation modelling (SEM), this study aims to investigate the relationships of economic factor and decision-making process with the choice of international academic destination. Results, conclusions, and recommendations are discussed.

Johnny amora

Social bots are computer programs created for automating general human activities like the generation of messages. The rise of bots in social network platforms has led to malicious activities such as content pollution like spammers or malware dissemination of misinformation. Most of the researchers focused on detecting bot accounts in social media platforms to avoid the damages done to the opinions of users. In this work, n-gram based approach is proposed for a bot or human detection. The content-based features of character n-grams and word n-grams are used. The character and word n-grams are successfully proved in various authorship analysis tasks to improve accuracy. A huge number of n-grams is identified after applying different pre-processing techniques. The high dimensionality of features is reduced by using a feature selection technique of the Relevant Discrimination Criterion. The text is represented as vectors by using a reduced set of features. Different term weight measures are used in the experiment to compute the weight of n-grams features in the document vector representation. Two classification algorithms, Support Vector Machine, and Random Forest are used to train the model using document vectors. The proposed approach was applied to the dataset provided in PAN 2019 competition bot detection task. The Random Forest classifier obtained the best accuracy of 0.9456 for bot/human detection.

Chandra sekhar sanaboina

This paper addresses global supply chain management (GSCM). The industry used to explore this topic is the automotive industry, as it is a core industry in the world economy, both in revenue generation and inefficiency. The paper explores both the positive and negative attributes of supply chain management, explores and analyses the gap between evaluation and implementation of improvements in supply chain management and then looks into the global issues affecting supply chain management and their solution.

Mohamed sorogy

The concept of knowledge and the process of knowledge sharing in ethnic minority microbusinesses remain neglected in contemporary debates even if their role for economic development is recognized. Drawing on a culturalist view, we explore how knowledge is defined and shared in a local niche market. Thematic analysis of semistructured qualitative interviews with 32 owner managers and 11 employee-managers reveals that, contrary to studies on larger firms, local knowledge creation and sharing narrowly based on ethnic strengths are valuable sources of competitive advantage. Our study has implications for researchers, policymakers, and practitioners in exploring, supporting, and integrating ethnic minority microbusinesses.

Muhibul haq

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in humans. It is characterized by excessive cell growth, accelerated intrusion of normal brain tissue, and a poor prognosis. The current standard of treatment, including surgical removal, radiation therapy, and chemotherapy, is largely ineffective, with high mortality and recurrence rates. As a result, traditional approaches have evolved to include new alternative remedies, such as natural compounds. Aquatic species provide a rich supply of possible drugs. The physiological effects of marine peptides in glioblastoma are mediated by a range of pathways, including apoptosis, microtubule balance disturbances, suppression of angiogenesis, cell migration/invasion, and cell viability; autophagy and metabolic enzymes downregulation. Herein, we address the efficacy of marine peptides as putative safe therapeutic agents for glioblastoma coupled with detailed molecular mechanisms.

Dr. salman ahmed

Background: COVID-19-positive patients are at increased risk of adverse clinical outcomes, with type 2 diabetes cohorts at substantially higher risk compared to the general population. The additional role of diabetic and non-diabetic polypharmacy in these patients' clinical course has remained unexamined. In this study we have comprehensively examined the role of polypharmacy in the determination of mortality outcomes in patients with COVID-19 clinical syndrome. Methods: We retrospectively examined case notes and electronic records of N = 497 patients with type 2 diabetes and COVID-19 infection. We ascertained the number of medications each patient was taking and used this to categorize the study cohort into diabetic [n = 246] (5 or more diabetic medications), and non-diabetic polypharmacy [n = 251] (5 or more non-diabetic medications). The primary outcome was the need for intensive care admission between the two groups. Results: In patients with “non-diabetic polypharmacy” (>5 medications), advancing age, and higher HBA1c levels, were associated with increased risk of Intensive care admission (OR 1.06 [CI 1.03-1.07], P = <0001), (OR 1.01 [CI 1.01- 1.20], P 0.017), respectively. Patients taking 5 or more non-diabetic medications had an increased likelihood of admission into the intensive care unit compared to those on lower medication thresholds (OR = 1.7; CI = 1.1 to 1.3; p-value = <0.0006). Conclusion: In an inpatient cohort of type 2 diabetic patients with COVID-19, non-diabetic polypharmacy was associated with a multiplicative risk of intensive care admissions. This will necessitate the need for periodic medication reviews in these cohorts of patients to mitigate these potential risks and improve clinical outcomes.

Karishma

Urolithiasis arises from disturbances in the urinary tract's physicochemical balance and hydrodynamic system. Medicinal plants have been known for millennia and are highly esteemed worldwide as a rich source of therapeutic agents for the prevention of various ailments. A comprehensive literature search of antiurolithiatic plants reported worldwide revealed the family Fabaceae with the highest number of cited species. The members, Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn. and Phaseolus vulgaris Linn. have been selected and hidden versatile weapons of their seeds against urolithiasis such as analgesic, antioxidants, astringent, diuretic, emollient, high soluble oxalate contents, insoluble fibers, magnesium, potassium, phytic acid, pyridoxine (vitamin B6), have been discussed on a scientific basis to rationalize the folkloric use.

Dr. salman ahmed

For thousands of years, lipid based Ayurvedic formulations have been made in India, and the craft has survived down the millennia up to the present time. Some of these deliciously potent phytonutrient preparations are very popular and have sustained the test of time pertaining to their efficacy. Recent researches on the role of phytonutrients in promoting cardio-pulmonary, brain and immune health substantially buttress the philosophy underlying the use of lipids in preparing these emulsions, since a large number of these bioactives are lipophilic. Being lipoidic, they are absorbed through the lacteals in the small intestine, and are then transported through the thoracic duct directly to the heart, bypassing the liver. The formulations utilizing ghee (clarified butter) or sesame oil as the carrier lipid, either while frying the myrobalams or as Anupana (adjuvant), have special significance in modulating bodily immunity, since the immune system is housed in lymphatics which are lipid rich. Amla and lipid based Ayurvedic rasayans (rejuvenating formulations) are a popular and highly palatable group of phytonutraceutical preparations. This group of polyherbal adaptogenic formulations is classified separately from other formulations in Ayurvedic therapeutics. Several of these healthpromoting rasayans are suitable to be consumed by all age-groups in the recommended season and dose. Current research on endothelial and immune cell receptor mediated uptake of lipoidic molecules, together with the knowledge of lipid absorption pathways, lends credence to the usefulness of rasayans in targeting the cardio-pulmonary and immune systems. An attempt has been made in this paper to elucidate the mechanisms underpinning the complex interplay between lipid delivered hydrophobic phyto-molecules, systemic lymphatics and the Immune system.

Sharadendu bali

This study investigated the practice of artificial fruit ripening among fruit vendors of banana, plantain, mango and pawpaw in Rivers State. The study adopted a descriptive cross-sectional survey design. Two objectives, corresponding research questions and null hypotheses guided the study. The population for the study comprised all the accessible 1,810 fruit vendors in Rivers East senatorial district. A sample size of 472 fruit vendors was drawn using multi-stage sampling procedure. A validated self-structured questionnaire titled ‘Practice of Artificial Fruit Ripening’ with inter-scale reliability co- efficient of 0.896 was used as instrument for data collection. The descriptive statistics of mean and standard deviation were used to answer the research questions, while inferential statistics of Z-test and One-Way Analysis of Variance were used to test the hypotheses at 0.05 alpha level. It was found that fruit vendors in Rivers State sometimes practiced artificial fruit ripening using chemical and non-chemical methods. It was also discovered that regardless of their level of education and years of experience in the fruit business, the fruit vendors sometimes indulged in unhealthy practice of artificial fruit ripening. More so, the study revealed significant difference in practice among the fruit vendors in Rivers State based on level of education and years of experience. Based on the findings, it was concluded that the current practice of artificial fruit ripening in Rivers State is not in tandem with global best practices and therefore portend danger to the wellbeing of Rivers people and other Nigerians. The study therefore recommended among others that; community health workers should carry-out regular and effective health awareness campaigns concerning the dangers of using chemicals to ripen fruits. The Government of Rivers State through the Ministry of Agriculture should organise training programmes for fruit vendors on faster, safer, and economically feasible methods of fruits ripening and other post-harvest management techniques

Fxintegrity publishing

Background: Pulses are well known richest source of vegetable protein and is known as poor man’s food because of its essential component in diet. The frontline demonstrations of pulses were carried out on 311.8 ha area with 694 demonstrations in different clusters of Nagaur district of Rajasthan. Methods: Front line demonstrations on chickpea, mung bean and moth bean crop were conducted by Krishi Vigyan Kendra, Nagaur-I, Agriculture University, Jodhpur during rabi and Kharif season of 2011-12 to 2019-20. Result: In demonstrations up to 29.43%, 30.29% and 35.22% yield increase of chickpea, mungbean and moth bean crop was observed over the farmer’s practices in the year 2011-12, 2017 and 2016. The yield gap between improved technology and conventional farmer’s practices was ranging from 1.98 to 4.54 q/ha, 0.61 to 2.55 q/ha and 0.6 to 1.68 q/ha, respectively. Whereas, the highest net returns of ` 71,881 ha-1 , ` 45,884 ha-1 and ` 14,315 ha-1 was observed in the year 2019-20, 2014 and 2016, respectively with the highest incremental cost benefit ratio of 1:3.71, 1:3.95 and 1:1.97 under demonstrations practices.

Dr. babu lal jat

A novel, simple, accurate, sensitive, reproducible, economical and less time consuming spectroscopic method was developed and validated for determination of cefixime. The solvent used was 0.1 N HCL and the absorbance maxima or the λmax was found to be 283.0 nm and 303nm for zero order and first order derivative respectively. This method obeyes Beer’s Law for the concentration range of 8–16 µg/ml for cefixime. The proposed method was been validated statistically as per the ICH guidelines for linearity, accuracy, precision, specificity, LOD and LOQ. The method developed and validated successfully for the quantitative analysis of cefixime in bulk and dosage form.

Prasanna pradhan

Various types of security attacks are normal in vehicular communication networks. The current study uses a support vector machine to implement a Point to Point Critical Path Monitoring (P2PCPM) based Denial of Service (DOS) Attack detection technique for Vehicular Communication Network (VCN) resource management. Greatest quality of P2PCPM is that it eliminates attacked nodes from the network for the smooth process of vehicular communication. This scheme works well in terms of accuracy as well as attack detection rate. The whole simulation is made and tried by utilizing MATLAB Software. Simulation result shows 99% accuracy in case of security attack detection as well as reduced training and testing error upto 2%. Experimental results indicate that this scheme has a great efficiency and works well up to 1000 nodes, which is the limitation of current implementation. In future, simulation test may be done for unlimited nodes using similar or other techniques of attack detection.

Vartika agarwal

Abstract: This study was conducted on two groups of broiler , the first consists of 4 replicates of 10 birds and the second of 10 birds as each bird is a replicate in individual cages. The first group were reared on floor during the entire period ,while the second was reared in cages during the period from 2-7 weeks of age. All birds received the same ration with 2859 Kcal/ kg ME and 22% CP as a starter ration, 2995 Kcal/kg ME and 19.19% CP as a finisher ration. The results showed that cage birds had a significantly (P≤0.01) higher body weight , total and daily weight gain at all ages , significantly(P≤0.01) higher total and daily feed and protein consumption , at 2- 4 , 0-4 weeks , feed and protein conversion ratio at 4- 7, 0- 7 weeks. Also cage birds showed a significantly better growth rate at 2- 4 , 0- 7 weeks and less dressing percentage, higher wing percentage while other carcass parts did not differ significantly. The cage birds showed better economic efficiency by 27% comparing to floor birds.

Rafea mohammedtaher khulel