Education is power. It constitutes the foundation of all the multidimensional socio-economic development of a country. In the present context, we need manpower or human capital for generating the growth and development in a country. The Government of India has taken several many initiatives for promoting education at all the stages i.e. Primary, Secondary and Higher. But still, we find such issues as a high dropout rate at all the stages of education, rural-urban disparity, gender disparity, interstate variations pose as some of the problems that impedes the development of human resources in our country. Even the work participation rate in India indicates the necessity of proper planning of skill training and employment opportunity. Most interestingly, the existing general and conventional higher educational institutions have not effectively been able to cope with the contemporary challenges and changes with the result that the nature of curriculum which is by and large in place tends to create only degree inflation in our country. So, we need such institutes and institutional arrangement that can cater to the contemporary challenges so as to upgrade the quality of education as well as to provide need based educational programmes that can develop human power in the society. Effective or quality education especially at higher level can play a vital role in bringing around multifaceted human resource development, enabling the learner’s absorption in the job market and selfemployment. This paper will discuss how the accessibility of education can be promoted to all through a convenient mode of education system and how the disparities in education can be minimized, and also focus on the various strategies for strengthening higher education system in the country.

Dr gedam kamalakar

Regularly used toothbrushes can be heavily contaminated with microorganisms, while inappropriate storage may increase the microbial load on these toothbrushes. Toothbrushes Microbial contamination can help to transmit many diseases, especially for people with mouth and/or Gum problems. This study aims to find the easiest and most available way to sterile toothbrushes at home. 24 adult volunteers were divided into four groups, the first three groups were asked to sterilize their toothbrushes with Dettol, water salt and hot water, while the fourth group toothbrushes were a positive control. Results showed that toothbrushes sterilized with Dettol gave the least contamination rate of 12.5%, toothbrushes sterilized with salt came next with 37.5%, while toothbrushes sterilized with hot tap water were the next with 50%. The toothbrushes of the fourth group which was used as the positive control were totally contaminated with different types of bacteria. Six bacterial agents were isolated; they are Staphylococcus Sp., Streptococcus sp., Bacillus Sp., E.coli, Pseudomonas Sp., and Salmonella sp. It was concluded that the use of Dettol was very effective in reducing the number of contamination of toothbrushes but its unacceptable flavour limiting its use. Other volunteers were comfortable with the use of salt and hot water as it was almost effective. The research suggests a group of recommendations to avoid the transmission of pathogens through toothbrushes and ensure healthy usage.

Kamal singh

Objective: This study was conducted to investigate traditional beliefs and practices of women regarding care of the mother and the infant during pregnancy, in childbirth, and in the postpartum period. Methods: This was a descriptive, cross-sectional study conducted at a public hospital in Istanbul. The data collected consisted of socio-demographic and obstetric characteristics, and responses to questions about some traditional customs regarding pregnancy, delivery, and the postpartum period. Results: In our research, some non-harmful cultural practices were found, such as the belief that to have a clever and beautiful baby the mother should eat fruit; that to have a healthy and peaceful pregnancy, the mother should not look upon ugly things; the mother should indulge her food cravings; and to have an easy birth, the mother should walk and focus on prayers. On the other hand, we also found beliefs that could be harmful, such as wiping the mouth of a baby with a date before breastfeeding, and practices believed to be protective that could cause harm, such as putting a knife under the baby’s bed, fastening a safety pin to the baby’s clothes, and for the mother and child to remain at home for 40 days. Conclusion: While non-harmful and beneficial practices related to maternal and infant health should be accepted and supported as a part of our cultural richness, practices that could be harmful should be prevented in pregnancy classes or with training upon hospital discharge

Reyhan aydin doğan

Background: Preterm birth remains a leading cause of neonatal morbidity and mortality worldwide. Identifying its risk factors is essential for developing targeted interventions to improve maternal and neonatal health. This study investigated the sociodemographic, obstetric, medical, and lifestyle risk factors associated with preterm birth among women who delivered at Abia State University Teaching Hospital (ABSUTH), Aba, Southeast Nigeria. Methods: A hospital-based case-control study was conducted at ABSUTH. The study population comprised all the women who gave birth at the facility who met the criteria. Data were collected through structured interviewer-administered questionnaires and medical record reviews. Key variables included maternal age, education level, socioeconomic status, obstetric history, medical conditions, lifestyle factors, and antenatal care utilization. Descriptive statistics, chi-square tests, t-tests, and logistic regression were performed using SPSS version 25, with statistical significance set at p < 0.05. Results: A total of 9125 deliveries were recorded during the period of this study, including 1,962 cases (preterm births, <37 weeks gestation) and 7,163 controls (term births, ≥37 weeks gestation). Chi-square analysis showed significant associations between preterm birth and maternal age (p < 0.05), low education level (p < 0.001), low socioeconomic status (p = 0.0351), previous preterm birth (p < 0.001), short pregnancy interval (p < 0.001), hypertension (p < 0.001), diabetes (p < 0.001), infections (p < 0.001), smoking (p < 0.001), alcohol consumption (p < 0.001), and inadequate antenatal visits (p < 0.001). Logistic regression confirmed that hypertension, diabetes, infections, previous preterm birth, and inadequate antenatal visits were independent predictors of preterm birth. Conclusion: The findings highlight the multifactorial nature of preterm birth, with medical conditions, lifestyle behaviors, and inadequate antenatal care playing crucial roles. Early identification and management of these risk factors through improved maternal health services and health education may reduce the burden of preterm birth in the study setting.

Karishma

Transglutaminase 2 (TG2) is an inducible transamidating acyltransferase that catalyzes Ca2+-dependent protein modifications. TG2 enzyme disruption has been implicated in several different disease processes and disorders such as Huntington and Parkinson’s diseases, cancers such as breast, ovarian and pancreatic cancers. Coeliac disease (CD) is the one disease state that TG2 activity plays a crucial role. To date, a gluten-free diet is the only accepted form of therapy for CD. Because of the important role of TG2 enzyme in the initiation of CD, therefore, this study was aimed at the identification of TG2 inhibitors from natural sources, as a potential intervention in CD therapy. Competitive amine inhibitors are the most widely used TG2 inhibitors because they are commercially available, chemically stable and relatively non-toxic in living systems. The natural products chosen for this study were dietary flavonoids. Flavonoids were extracted from different food samples. The flavonoids food extracts were subjected to the TG2 activity assays to examine their effect on the enzyme activity. The assays were carried out under optimal conditions of pH, Ca2+ and with N, N-dimethylcasein (acyl-donor) or casein (acyl-acceptor) as acyl-donor substrates and biotin cadaverine (acyl-acceptor) or TVQQEL as (acyl-donor) substrates. TG activity was measured by two different microplate assays, Biotin-labeled cadaverine incorporation assay and Biotin-labeled peptide cross-linking assay. In the TG2 amine incorporation activity, all of food extracts display a significant inhibition effect towards the human recombinant transglutaminase2 (hrTG2) and guinea pig transglutaminase 2 (gplTG2) (20 - 50% of inhibition). While in the TG2 cross-linking activity, the majority of food extracts displayed an inhibition effect on the gplTG2 cross-linking activity (50 - 70% of inhibition) but only the strawberry and kale extracts showed an effect on hrTG2 activity (40 - 50% of inhibition). The inhibition of TG2 activity can be considered as a potential therapeutic target in the treatment of CD.

Mediterranean journal of pharmacy and pharmaceutical sciences

Now a day’s contribution of Electronic banking towards economic development plays a crucial role in developing countries like India. Banks are no longer restricted to traditional banking rather it is shifted to the virtual banking system. Customers are experiences more feasible in banking operations because of Information technology. The banks are adopting IT-enabled tools and techniques for banking operations which improve in offering quality service to the customers. In traditional banking customers has to visit bank branches to avail banking services. Now with the ATMs, Internet banking, Mobile banking and Information Technology-enabled services are replacing the traditional method of service. In the recent days banks are concentrating on value-based service through E-banking. The present study throws a light on the growth of Electronic banking and its product which are used in the banking sector.

Kamal singh

Parkinson’s disease is a common movement disorder associated primarily with oxidative stress-mediated degeneration of dopaminergic neurons. Earlier studies showed that Sorghum bicolor-based supplement (SbS) exhibited antioxidant and neuroprotective activities and might likely rescue the death of dopaminergic neurons in Parkinson’s disease. This study examined the effect of SbS on rotenone-induced Parkinsonian-like motor deficits in rats and the involvement of oxidative stress and pro-inflammatory cytokines. Rats were divided into six groups and treated orally with sunflower oil (vehicle-control), rotenone (2.5 mg/kg) alone or in combination with each dose of SbS (50, 100, and 200 mg/kg) and levodopa-carbidopa (10 mg/kg) on an alternate day for 28 days. The changes in motor functions were evaluated on day 28 and the brain concentrations of oxidative stress biomarkers and pro-inflammatory cytokines (tumor necrosis factor-alpha and interleukin-6) were determined. Rotenone caused motor deficits by impaired locomotor activity in the open field test and induced catalepsy in the bar test, which were attenuated by SbS. Rats pretreated with SbS had reduced brain levels of malondialdehyde, nitrite, and pro-inflammatory cytokines compared to rotenone controls. SbS mitigated rotenone-induced depletion of reduced glutathione and antioxidant enzymes in the rat brain. The results suggest that SbS ameliorated rotenone-induced Parkinsonian-like motor dysfunctions by reducing neuronal oxidative stress and pro-inflammatory cytokines in rats.

Mediterranean journal of pharmacy and pharmaceutical sciences

This study intends to describe assessment strategies for young students' online learning. The participants in this descriptive qualitative study were 15 primary school principals and 35 teachers teaching Years 4 and 5 in urban and rural schools on the island of Lombok, West Nusa Tenggara Province, who volunteered their participation after undergoing comparable procedures. Using operational concepts of assessment of learning for online learning, class observation, and interview were organized. The content and structure validity of the measures were evaluated in accordance with the developmental periods of young learners. The findings showed that the teachers assessed the primary students' cognitive, psychomotor, and affective domains interactively during the online class meetings, in their portfolio, and through attitude direct observation. Several assessment strategies were advocated to circumvent the shortcomings of online learning. A criterion-referenced evaluation was used to conduct the analysis. The theoretical implications of the findings suggest that the various assessment procedures adopted have decreased the negative washback of online exams; however, further research is required to determine the consistency of the outcomes of online tests with other types of evaluation.

Darrel ocampo

Background: Unexplained infertility is a frustrating diagnosis both for the patient and the clinician, with a prevalence of 16%-37%. It commonly refers to a ‘diagnosis’ made when tubal, ovulatory and husband factors are ruled out. A couple is usually referred for evaluation after 1 year of unsuccessful trials of conception with unprotected intercourse in the fertile phase of the menstrual cycle. Unani formulation comprises of baikh asgand (Withania somnifera Dunal), baikh piyabansa (Barleria prionitis Linn), gule dhawa (Anogeissus latifolia) and gule nilofar (Nymphaea alba Linn) were used for the treatment of uqr, possessing the properties of muqawwi rahim, moaene hamal, moallide mani, etc. Case presentation: A married couple (22 years female partner & 26 years male partner) presented to NIUM Hospital OPD, with chief complaint of failure to conceive since 5 years. The couple report a high degree of stress related to their lack of success. Investigations were carried to check for tubal patency, ovulatory function and semen analysis. Diagnosis of unexplained infertility was made after thorough evaluation of the case. The powder of above mentioned formulation was given 6g twice a day orally with milk from 5th day of cycle for 5 days. Patient got conceived after taking treatment for two consecutive cycles. Discussion: Here we report evidence based management with Unani medicine to help combat the significant physical, psychosocial and economic toll on couples. Keywords: Unexplained infertility; Primary infertility; Uqr; Muqawwi rahim; Moaene hamal; Moallide mani; Unani medicin

Dr ismath shameem

Abstract: This study was conducted on two groups of broiler , the first consists of 4 replicates of 10 birds and the second of 10 birds as each bird is a replicate in individual cages. The first group were reared on floor during the entire period ,while the second was reared in cages during the period from 2-7 weeks of age. All birds received the same ration with 2859 Kcal/ kg ME and 22% CP as a starter ration, 2995 Kcal/kg ME and 19.19% CP as a finisher ration. The results showed that cage birds had a significantly (P≤0.01) higher body weight , total and daily weight gain at all ages , significantly(P≤0.01) higher total and daily feed and protein consumption , at 2- 4 , 0-4 weeks , feed and protein conversion ratio at 4- 7, 0- 7 weeks. Also cage birds showed a significantly better growth rate at 2- 4 , 0- 7 weeks and less dressing percentage, higher wing percentage while other carcass parts did not differ significantly. The cage birds showed better economic efficiency by 27% comparing to floor birds.

Rafea mohammedtaher khulel

Marketing has now adopted technologies in the attempt to increase brand recognition. Due to the COVID-19 pandemic, many companies suffer, yet many even reap more profits, such as e-commerce. The purpose of this research is to figure out whether Celebrity Endorsement, Advertising Appeal, and Electronic Word of Mouth have influence towards customer’s Purchase Decision in one of popular e-commerce in Indonesia called Bukalapak. Through the non-probability sampling type, particularly purposive sampling approach, one hundred respondents are taken as samples. The method in this research is descriptive and causal, and the research type is quantitative research. The data analysis methods used are descriptive statistics, coefficient of correlation, coefficient of determination, linear regression analysis and hypothesis testing through T-Test and F-Test. The T-test shows that Celebrity Endorsement, Advertising Appeal, and Electronic Word of Mouth partially influence the Purchase Decision. The F-Test result shows that all independent variables simultaneously influence Purchase Decision. Out of all, Celebrity Endorsement has the biggest influence on Purchase Decision. The value of coefficient of determination obtained is as much as 80.6% indicating that the customer’s Purchase Decision in Bukalapak is explained by Celebrity Endorsement, Advertising Appeal, and Electronic Word of Mouth. The recommendation given is to ensure the company uses talented and well-known celebrity endorsers, design attractive and unique advertisement, and maintain satisfactory performance to encourage complimentary reviews on its platform.

L

Various quality control tests are employed for solid dosage forms such as uniformity, dissolution and drug contents in order to assess their pharmaceutical equivalence. The objective of the current study was to assess and contrast five distinct metformin hydrochloride brands that are offered for sale in the Libyan market. The physicochemical equivalence of the five brands of metformin hydrochloride tablets (500 mg) were determined through the evaluation of official and non-official standards according to the USP including uniformity of weight, friability, hardness, dissolution rate and drug content. All the examined brands available in the Libyan market passed the official weight variation, friability, dissolution and disintegration tests and were equivalent. The friability test was found within the specified limit. All the formulations were disintegrated within 09 - 15 min. The tested brands were non-equivalent to the innovator Glucophage® according to their dissolution evaluation. The percentage content of the active ingredient of five brands of metformin tablets showed values within the monograph specifications (95% - 105%). In conclusion, all the five brands available in the Libyan market which were evaluated in this study cannot be substituted with the innovator product in clinical practice.

Mediterranean journal of pharmacy and pharmaceutical sciences

Keeping an in depth tab of recent folks or folks on chair with bound health conditions for his or her health and safety is a very important task. With maturity, weak bones and weakness because of alternative health connected problems could lead to will increase risk of falling. A supervisor might not continually be on the market with them and if correct assistance is not provided at the correct time it should cause larger health considerations which will need extra resources for treatment. For this purpose we've projected a wise IOT Fall Detection System exploitation acceptable sensors that square measure integrated facilitate|to assist} report these incidents to assist avail help at the correct time to forestall additional injury to health. The same system uses sensors like associate degree measuring system to live the speed of the person, a rotating mechanism to live the person’s orientation so as to live their stability, a load sensing element once the system is employed by an individual employing a chair to live their weight, a Wi-Fi module and a microcontroller that sends the general readings to alert the involvedthose that shall give with the right suggests that to assist the person in want. The microcontroller receives all the info from the sensors and perpetually transmits and monitors the acceleration and also the orientation of the person. Any fast abrupt modification within the system which will result from a fall is taken into account as a ‘fall’ and is reported . a serious concern would be that not all fast movement may end up from a fall and be thought of as a matter of concern. To avoid this warning a napbutton is provided to snooze the system. This button will be ironed before a definite time say 15-30 seconds to prevent the system from causation the alert, thus avoiding any confusion and panic. this method will be mounted to the person’s chair or will be created compact to be created into a wearable device which will be worn on the hand.

Dr h shaheen

The decision of the government of India to allow foreign direct investment in higher education is based on a consultation paper prepared by the commerce ministry, which is marked by arguments, perverse logic and forced conclusions. FDI in any field does not have an attached objective of fulfilling social agenda of the welfare state. It is guided by profit and market. This would result in commoditization of education. As per past most foreign institutes invest in technical courses which market needs rather than in quality education and research which is important for creating and developing human resource. There is a shortage of funds in higher education sector. Here are not many ways in which this investment in this sector can be increased in this sector domestically. Since a large number of students go abroad for their higher education, it is sensible to allow foreign universities to set up their campuses here, in India. This would help in arresting the outflow of monetary and human capital. Further, foreign higher educational institutes would create competition with the local institutes making them internationally competitive this article examines the issues and financial compulsions, presented in the consultation paper

Dr gedam kamalakar

Water contamination has become a global challenge which must be tackled. This study examined the contamination level of water in four locations at Ogbete area Enugu state. Carters street had the highest pH of 5.23 which is below the WHO standards limits for drinking water. The conductivities ranged from the highest conductivity 1445 μs/cm, which is below the WHO limits (8-10,000 μs/cm), TDS (1000 mg/l., TSS (WHO (500 mg/l). For alkalinity, the four locations were all below the (150 mg/l) standard set by World Health Organisation. Results showed that most of the physicochemical, biological and heavy metals parameters considered in this study were significantly above the permissible or allowed by WHO. It is therefore recommended that the water should be treated before use.

Okechukwu obed chukwuemeka

This research was conducted to form students to be more disciplined in maintaining time, especially in prayer, as well as to strengthen aqidah and increase the worship of students of Madrasah Ibtidaiyah Salafiyah Syafi'iyah. The focus of this research is: 1) How to plan the prayer chapter of fiqh learning through audio-visual media for students of Class IV Madrasah Ibtidaiyah Salafiyah Syafi'iyah Ajung, 2) How to implement the prayer chapter of fiqh learning through audio-visual methods for students of Class IV Madrasa Ibtidaiyah Salafiyah Syafi 'iyah Ajung, 3) How is the evaluation of fiqh learning in the prayer chapter for fourth grade students of Madrasah Ibtidaiyah Salafiyah Syafi'iyah Ajung. This research uses qualitative research with descriptive qualitative research. Determination of research subjects in this study was carried out purposively. Data collection techniques used observation, interviews, and documentation. Analysis of the data, the researcher used the data analysis model of the Miles, Huberman, and Saldana models including: Data Condensation (Condensation), Data Presentation (Display), Conclusions Drawing. The validity of the data in this study used source triangulation and technical triangulation. The results showed that: 1) The use of audiovisual media was very relevant in learning fiqh in the prayer chapter 2) Active, innovative, creative, effective and fun learning made students enthusiastic and enthusiastic in learning and not boring. 3) the completeness of learning facilities and infrastructure is very influential in the evaluation stage including summative evaluation and formative evaluation, input evaluation, process evaluation and output evaluation. Penelitian ini dilakukan untuk membentuk peserta didik lebih disiplin dalam menjaga waktu khususnya dalam shalat, serta memantapkan aqidah dan meningkatkan ibadah peserta didik Madrasah Ibtidaiyah Salafiyah Syafi’iyah. Fokus penelitianini adalah: 1) Bagaimana Perencanaan Pembelajaran fiqih bab sholat melalui media audio visual bagi peserta didik Kelas IV Madrasah Ibtidaiyah Salafiyah Syafi’iyah Ajung, 2) Bagaimana Pelaksanaan pembelajaran fiqih bab sholat melalui metode audio visual bagi peserta didik Kelas IV Madrasah Ibtidaiyah Salafiyah Syafi’iyah Ajung, 3) Bagaimana evaluasi pembelajaran fiqih bab sholat bagi peserta didik kelas IV Madrasah Ibtidaiyah Salafiyah Syafi’iyah Ajung. Penelitian ini menggunakan penelitian kualitatif dengan jenis penelitian kualitatif deskriptif. Penentuan subyek penelitian dalam penelitian ini dilakukan secara purposive.Teknik pengumpulan data menggunakan observasi, wawancara, dan dokumentasi. Analisis data, peneliti menggunakan model analisis data model Miles, Huberman, dan Saldana meliputi: Kondensasi Data (Condensation), Penyajian Data (Display), Penarikan Kesimpulan (Conclusions Drawing). Keabsahan data dalam penelitian ini menggunakan triangulasi sumber dan triangulasi teknik.Hasil penelitian menunjukkan, bahwa: 1) Penggunaan media audiovisual sangat relevan dalam pembelajaran fiqih bab sholat 2) Pembelajaran aktif, inovatif, kreatif, efektif, dan menyenangkan membuat peserta didik semangat dan antusias dalam belajar serta tidak membosankan. 3) kelengkapan sarana dan prasarana pembelajaran sangat berpengaruh pada tahap evaluasi meliputi evaluasi Sumatif dan evaluasi Formatif evaluasi input, evaluasi proses dan evaluasi output.

Educare: journal of primary education

Is open theological education reducing barriers and increasing access to theological training? Has the use of digital technologies in accessing theological training deviated from or complied with the training criteria? This paper highlights the seminarians’ borderless access to theological education and its benefits. Several persons frowned on open education a few years ago, but from March 2020, the COVID-19 pandemic has seen many institutions adopting elearning. Is it a wake-up call for theological education? The study discovered that theological education without barriers enhances theological training, research writing, scholarship, and academic honesty. The accreditation criteria for open theological learning does not alter contents but ensures that the greater populace can access a high standard of delivery of theological training equal to the on-campus programmes.

Ransford k awuku-gyampoh

Formulation of the least cost rations that provides the nutrient requirements of birds is an important goal in poultry production . The aim of the present study was to create an application in the Excel program for formulation of low-cost poultry diets that provide adequate nutritional requirements using linear programming based on the Solver function of the Excel program and composition of common feed ingredients used in poultry diets (yellow corn, wheat, soybean meal , barley, wheat bran, protein concentrate, limestone, table salt, di-calcium phosphate, vitamins and minerals premix ,and vegetable oil), if their default prices are 500, 450, 750, 350, 250,1750, 250, 100, 500, 4500,and 1500) Iraqi Dinar / kg, respectively. The results showed that the Solver function in - Excel can be used to solve linear programming models such as those used for formulation of least cost poultry rations. This Microsoft Excel application is ready to use and can be used to assist researchers and students in formulating poultry rations that provide the desired nutritional requirements of poultry at the lowest cost. Key words : Application

Rafea mohammedtaher khulel

Rural Self Employment Training Institutes (RSETIs) functions as a structural framework for skill development & entrepreneurship development training laid down by Ministry of Rural Development, Government of India in the year 2009. The concept of RSETI is bagged from the RUDSETIs (Rural Development & Self Employment Training Institutes), the brain child of Dr. D. Veerendra Heggade. RSETIs have 65 approved courses as per National Skill Qualification Framework (NSQF) under which they offer different types of Entrepreneurship Development Programme (EDP). All the programmes are short term residential training with 2 (two) years hand holding support. State Level Bankers Committee data revealed that through the RSETI training, huge number of unemployed youths started their own enterprise with or without bank finance and also getting the scopes of Self-employment. This particular study took a humble effort to publicize the role of TGB-RSETI in Tripura in respect to unemployment reduction through entrepreneurship development. The entire study is based on secondary data (2009-10 to 2022-23) retrieved from SBLC, Tripura website data.

Md. abdur rahman choudhury

Background: Preanalytical variability due to anticoagulant choice remains inadequately characterized in resource-limited tropical settings like Yemen, where environmental stressors exacerbate challenges. This study aimed to compare the stability and cost-effectiveness of K₂EDTA and K₃EDTA anticoagulants for complete blood count testing under simulated Yemeni conditions. Methods: Prospective study of 100 healthy adult male volunteers in Ad’Dla Governorate, Yemen (January–March 2025). Paired samples in K₂EDTA/K₃EDTA tubes were analyzed at baseline (T0) and after 6-hour storage at 22 ± 2°C (T6). Statistical analysis included Bonferroni-corrected repeated-measures ANOVA and paired t-tests. Results: Fresh samples showed high inter-anticoagulant concordance (ICC > 0.90). After 6-hour storage, K₂EDTA exhibited significant Mean Corpuscular Volume (MCV) reduction (Δ = −2.33 fL, p < 0 xss=removed xss=removed xss=removed> 2 hours), while K₃EDTA is preferable for immediate analysis. These findings provide preliminary guidance for hematology testing in Yemeni laboratories and similar tropical settings, pending validation in diverse populations and extreme conditions.

Karishma