Education and practice of pharmacy in libya

In Libya, pharmacy education and practice have a similar pattern to medical education and practice. Both sectors of public and private pharmacy education and pharmacy practice still significantly unchanged for more than forty years. It is a traditional pharmacy style of education and practice with a limited change of education and practice. Now, there are more than ten public pharmacy colleges and more than five private colleges established in Libya for a population of seven millions. In addition, there are several intermediate pharmacy institutes which provide a middle degree in pharmacy practice with a very limited knowledge in pharmaceutical sciences and training. Practice of pharmacy in Libya is still a classical mode with only dispensing medicines directly in almost a nonprofessional way and an old fashion way. However, the situation is old and complicated that needs a great deal of attention from different health policymakers and authorities such as Ministry of High Education and Ministry of Health, National Pharmaceutical Union and Libyan Association for Pharmacists.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Fragaria nubicola (rosaceae): a review of medicinal uses, phytochemistry and pharmacology

Fragaria nubicola (Hoof. f) Linn. (Rosaceae) is a medicinally important plant commonly called Wild strawberry. Traditionally, it has been used to treat different diseases. The study was carried out to compile all the previous data in review form based on its distribution, traditional medicinal uses, pharmacology and phytochemistry

Dr. Salman Ahmed Dr. salman ahmed

Assess the premenstrual symptoms and coping strategies among adolescent girls

Menstruation is a normal physiological impact on each girl’s life. Menstruation is monthly uterine bleeding for 3-5 days after every 28 days from puberty till menopause. A change in mood, behaviour, appearance of some abnormal vague symptoms is often noticed in the second half of the cycle. Symptoms are severe enough to disturb the life cycle of a woman called premenstrual syndrome (PMS). The study aimed to assess the premenstrual symptoms and coping strategies among adolescent girls. The majority of the students suffered from premenstrual syndrome. Objective: to assess the premenstrual symptoms and coping strategies among adolescent girls. Methodology: A nonexperimental descriptive research design was adopted in this study. Non probability convenient sampling technique was used to select the sample size of 30 adolescent girls. The assessment of premenstrual symptoms and coping strategies was carried out using a self-reported Likert’s rating scale. Data was analyzed by using descriptive and inferential statistics. Result: Majority (93.3%) of the samples sometimes had physiological and psychological problems, 90% of them had behavioural symptoms. Majority (43.3%) of the samples always followed coping strategies and 16.7% of the samples sometimes followed coping strategies and 40% never followed any coping strategies. Conclusion: PMS was common among students at 18-24 years. The most common physical symptoms experienced by adolescent girls were headache, backache and lower abdominal pain. Adolescent girls used coping strategies as taking hot / cold drinks, do not express anger to others, and turn to study and forget things, hearing music and taking medications. Keywords: Premenstrual Symptoms, physiological, psychological & behavioural symptoms, Coping Strategies, Adolescent Girls.

Elsi Queen Elsi queen

L’expression de la solitude à travers les chansons funéraires dans l’aire culturelle ajatado

Dans toute société, l’homme nait, grandit et meurt. Ces étapes marquant la vie de l’être humain sont des passages obligés dans le parcours existentiel de tout être vivant. Si le premier et le deuxième éléments sont des moments de réjouissance pour les parents, les amis et la famille, le troisième par contre attriste, alite et est parfois source de discorde et de séparation des membres d’une même communauté. A la mort d’un parent, des soutiens de toutes natures viennent de toute part. Ces soutiens sont la manifestation de la solidarité au sein de nos communautés. Des chansons sont scandées avant, au cours et après l’inhumation. Comme on le constate dans plusieurs communautés linguistiques, ces chansons funéraires assument, dans la société, des fonctions diverses. Cette étude qui analyse quelques chansons aussi bien sur le plan social que linguistique, vise à montrer la valeur de la chanson et le sens qu’elle véhicule dans la communauté ajatado prenant en compte le Bénin, le Togo, le Ghana et le Nigéria sans oublier ses différentes fonctions dans la société.

Assanvo

Preparation and evaluation of a thermoadhesive gel formula containing pioglitazone as a drug carrier to the brain through the nasal cavity

Background: Pioglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, has demonstrated potential in managing Alzheimer’s disease (AD); however, its oral administration is limited by systemic side effects such as cardiovascular risks and hepatotoxicity. This study aimed to formulate and evaluate a thermo-adhesive intranasal gel containing pioglitazone, utilizing Poloxamer 407 and Carbomer, as a targeted drug delivery system for AD. Methods: A series of gel formulations was prepared and assessed for gelling capacity, homogeneity, pH, and stability. The solubility of pioglitazone in various solvents was tested, and the optimal thermo-adhesive gel was selected based on gelation at physiological temperature (37°C–39°C). Results: The formulation containing 3 g Poloxamer 407 and 0.8 mg Carbomer successfully transitioned into a gel at body temperature and maintained physical stability over 2 months under accelerated conditions. The pH remained within the acceptable intranasal range (5.7–6.0), and no visual or olfactory changes were observed. Conclusions: The developed thermo-adhesive intranasal gel offers a promising alternative to oral pioglitazone delivery for AD, with the potential for enhanced Central Nervous System (CNS) targeting and reduced systemic side effects. Further toxicity and in vivo efficacy studies are warranted to confirm safety and therapeutic value.

Karishma Karishma

Analytical study of foreign direct investment in indian automobile sector

This research paper focused on the role of FDI in Indian automobile sector& dramatic changes in automobile sector after 1991’s open economy policy of Govt. This paper also attempt to splash light on some important aspects such as the journey of Indian Automobile sector from scratch to spectacular progress with combination of foreign technology & Indian talents, growth in direct & indirect employment, economic development of some important aspect in country like GDP as well technology transfer, improvement in R&D through the automobile clusters in country, focusing on potential of Indian automobile sector which is attracting Foreign investment.As well the policy support (Automobile mission plans 2006-16, 2016-2026, NATRiPS, Make in India Mission) by the Central & State Government for establishment of production facilities attracted automakers worldwide. As FDI is key driver not only in terms of inflow of FOREX but changes in the attitude of Government, Customers, &Automakers itself.

ANSHUMAN VIJAY MAGAR Anshuman vijay magar

Employees’ service innovation behavior and new service development in four- and five-star hotels

This study aims to explore the impact of Employee Service Innovation Behavior (ESIB) on New Service Development (NSD) among hotels’ employees. A research model was proposed in which one hypothesis was developed. The empirical data were collected from employees who are working in four- and five-star hotels in Jordan. A total of 332 questionnaires were returned and the data were analyzed using a single regression to determine the relationship between ESIB and NSD. The results supported the proposed model that there is a significant relationship between ESIB and NSD, and it also found that service innovation performance is exited in the hotel industry. The theoretical and managerial implications were drawn based on the study findings, and recommendations for future researchers were made, and limitations and conclusions are discussed.

Mukhles m. al-ababneh

Ethnopharmacology - the science behind herbal medicine discovery from ancient wisdom

Drug discovery started when a man suffered from abdominal pain and accidentally healed by chewing the leaves of the plant. The story of Ethnopharmacology begins with the doctrine of signatures, the shape signatures of herbs to heal resembled parts of the body. Later, shape signatures were modified into colour and taste signatures for healing. The information exchange and understanding about people's use of natural resources to discover therapeutic and toxicological potential is now shaped into a branch of science, "Ethnopharmacology". Simply Ethnopharmacology, by using modern science, enables traditional knowledge to convert into medicine and acts as a powerful and creative drug discovery engine.

Dr. Salman Ahmed Dr. salman ahmed

Organic ranking cycle–stirling engine efficiency in small scale industrial solar energy conversion in delta state, nigeria

This study analyzed the performance of hybrid ORC -Stirling systems in terms of thermal-mechanical energy conversion in relation to small-scale power generation by industries in Delta state, Nigeria. The two main parameters examined included the thermal collection efficiency of evacuated tube collectors and the influence of the environmental parameters on the stability of torque and the power output of the shaft. The data collection was performed on solar irradiance, ambient temperature, wind speed and PCM thermal cycling at 8-hour intervals in 90 days, and analyzed by means of MATLAB-simulated multidimensional plots. Findings showed that evacuated tube collection produced efficiency of ≥65% thermal collection efficiency, providing sufficient heat input for ORC–Stirling systems to maintain torque deviations within ±5% and conversion efficiency ≥40%. Mean solar irradiance of 775W/m²and PCM cycling between 250–310°C supported continuous 8-hour daily operation of industrial machinery. The results showed that hybrid ORC-Stirling systems are reliable to drive small-scale industrial processes even when environmental conditions vary. It was therefore advised that the small-scale operators should invest in ORC-Stirling systems, the Manufacturer Association of Nigeria (Delta State Chapter) should create awareness and demonstrations of this hybrid ORC-Stirling system and tertiary institutions in Delta state should engage the faculties of Mechanical Engineering to conduct training and pilot projects to facilitate adoption and proper maintenance of this ORC-Stirling system. Such measures will further improve operational stability, cut down-time and sustainability and decentralized industrial power

FXintegrity Publishing Fxintegrity publishing

Nano-catalyzed green synthesis of pyrazole derivatives & its biological activity as eac receptor antagonists

Different derivatives of Cinnamaldehydes were prepared by Claisen-Schmidt condensation (by using Strong basic reagent). The prepared Cinnamaldehydes were treated with Hydrazine hydrate in presence of ZnO Nano-catalyst under microwave assisted solvent-free conditions to afford different substituted Pyrazoles. Green chemistry was employed. Comparisons of both microwave & conventional methods were studied & found that the first was more potent than the later. The synthesized compounds were characterized by FT-IR, 1HNMR & elemental analysis. All synthesized compounds were screened for in vitro test against EAC cell lines. Most compounds exhibited good inhibitor potency with IC50 values.

Dr Ganesh N Yallappa Dr ganesh n yallappa

Marine peptides in breast cancer: therapeutic and mechanistic understanding

Breast cancer is the most prevalent invasive form of cancer in females and poses a significant challenge to overcoming the disease burden. The growth in global cancer deaths mandates the discovery of new efficacious natural anti-tumor treatments. In this regard, aquatic species offer a rich supply of possible drugs. Studies have shown that several marine peptides damage cancer cells by a broad range of pathways, including apoptosis, microtubule balance disturbances, and suppression of angiogenesis. Many side effects, including immune response suppression, characterise traditional chemotherapeutic agents. The discovery of novel putative anti-cancer peptides with lesser toxicity is therefore necessary and timely, especially those able to thwart multi-drug resistance (MDR). This review addresses marine anti-cancer peptides for the treatment of breast cancer.

Dr. Salman Ahmed Dr. salman ahmed

A study of foreign direct investment in indian pharmaceutical industry

Human being has some basic needs which include Food, Clothing & Shelter, in addition to above Healthcare, Education, Sanitation are also core part of basic necessities in modern society. In above mention basic necessities Healthcare facility was near to unavailable till independence for majority of citizens in country but this picture change dramatically with help of FDI allowed by Govt. of India. Foreign Direct Investment as a strategic element of funding is required in every develop & developing country. FDI inflows are long term in nature which causes source of non-debt finance, as well as bring modern & innovative technology in country by creating international network. In this paper, author attempted to discover how FDI is crucially impact on Indian Pharmaceutical Sectors progress by stimulating domestic investment & new employment opportunities, improving healthcare facilities to citizens in India. With the help of available relevant secondary data, a qualitative approach was followed for the study. It was found in study that the major factors responsible for attracting FDI in pharmaceutical sector are rise in outsourcing activities, demand in the generics market, demand from emerging segments, increase in domestic demand, large numbers of forthcoming patent expires. On the other hand Indian pharmaceutical industry is facing some challenges such as, low government expenditure on healthcare, poor healthcare infrastructure in rural areas, lack of proper Govt. policy to attract larger FDI in healthcare sector.

ANSHUMAN VIJAY MAGAR Anshuman vijay magar

Effect of pranayama on type 2 diabetes on metropolitan people

The purpose of the study was to find out the effect of pranayama on type-2 diabetes on metropolitan people. In the present study researcher wants to observe the effect of pranayama on type 2 diabetes on metropolitan people and to develop a specific package for type 2 diabetes. For this purpose researcher collect 60 sample from nearest diabetic Clinic and Hospital in the city and it is randomly divided into two groups one is experimental and another is control group. In the study researcher used bio-chemistry lab tools. In the study research design used Pre-test, post-test control-experimental group and researcher used two variable type 2 diabetes as dependent and pranayama used as independent variable and in the study there was significant effect of yogic practices on type 2 diabetes.

Shekhar Boro Shekhar boro

A study of special educators‟ knowledge of therapies"

Therapies highly plays a crucial role for all those children and adults with disabilities. In this article, We aim to research the Special Educators’ Knowledge about Therapies in various special schools in the city of Hyderabad, Telangana, India. A qualitative approach was taken for this purpose. Questionnaires was used to collect the data. It was found that the teachers did not have proper conception on Therapies. The data indicated that the teachers are unaware about the unconventional therapies such as Drama Therapy, Pet Therapy and Laughter Therapy and there benefits when working with CSN. This lack of awareness needs to be addressed for the enhancement of the teacher as well students capabilities.

Husna habib Husna habib

Employees’ perspectives of service quality in hotels

Although the importance of service quality has been recognised, few studies have addressed service quality in hotels from the perspective of employees. Therefore, this study aims to measure the service quality of four and five-star hotels in Jordan from the employees’ perspective based on the SERVQUAL model. The current study was carried out by measuring the data gathered according to a five-point Likert scale. A quantitative survey method was applied, and therefore the SERVQUAL instrument was used to measure service quality. Data obtained from a sample of 238 respondents drawn from ten four- and five-star hotels in Jordan were analysed with the SPSS software based on descriptive statistics. The study’s findings indicated that service quality of five-star hotels in Jordan was higher than that of four-star hotels.

Mukhles m. al-ababneh

"awareness and knowledge about refractive errors and strabismus in south indian population

Background: To assess the awareness, knowledge about refractive errors and strabismus among the general public in southern Indian states of Andhra Pradesh and Telangana. Methods: A cross sectional population-based survey used a semi structured questionnaire on awareness, knowledge on refractive errors and strabismus done as part of knowledge, attitude and practices study (KAP). Stratified multistage cluster random sampling method was used with a sample size of 867 adults- ≥16 years. Having heard of refractive error and strabismus was defined as awareness and having knowledge of the type of error for which spectacles were worn, was considered as knowledge. A pilot study was conducted to validate the questions used in the main study. Statistical package SPSS (version 19) was used for analysis to calculate logistic regression and odds ratios for gender, age, education and urban-rural areas. Results: A total of 782/867 (90.1%) subjects participated in the survey with females 47.4%. 581 subjects (74.3%) were aware of refractive error. 690 subjects (88.2%) were aware of squint. With multiple logistic regression about awareness of refractive error to various variables, subjects who were educated 11th class to degree had a higher awareness (OR: 2.40; CI: 1.25-4.60). With multiple logistic regression about awareness of squint to various variables, females had a higher awareness of squint (OR: 1.98; CI: 1.19-3.31). Conclusions: Awareness of squint and refractive error was high among the general public, but the knowledge of it was limited.

srinivasa reddy pallerla Srinivasa reddy pallerla

Chemical pharmacognosy in natural drug discovery-bridging folk wisdom and modern medicine

"Chemical Pharmacognosy" explores natural drug discovery, traversing from traditional remedies to modern therapeutics. This interdisciplinary approach aids biodiversity exploration, supports conservation, and validates Traditional, Complementary and Alternative Medicine. The significance extends to drug formulation, quality control, and combating drug resistance. Symbolizing a holistic journey, it bridges traditional wisdom with scientific innovation, playing a pivotal role in harnessing nature's chemical diversity for human health and guiding drug development.

Dr. Salman Ahmed Dr. salman ahmed

A comparative study of nurses' knowledge and attitude towards impact of oral cancer on oral hygiene and nutritional status of patients with oral cancer in selected general and cancer hospital at mysore and bangalore with a view to develop self-instru

Background: Cancer is burden for almost all societies in the world. It is estimated that approximately 20 million persons are suffering with cancer and every year 10 million die due to cancer. Methods: A descriptive and comparative survey from January 2024 to June 2024 with a quantitative research approach was used. The non-probability convenient sampling technique was used, and 60 nurses (30 each from Cancer Hospital; and General Hospital) had given consent for participation in the study. The tools used for data collection were personal profile, structured knowledge questionnaire, modified Likert-type attitude scale, and opinionnaire for utility of SIM. Results: The study found that 83.35% of General Hospital and Cancer Hospital nurses had strong knowledge, while 10% and 6.66% had low knowledge. All nurses from both institutions have mildly positive to extremely positive thoughts about how oral cancer affects oral hygiene and nutrition. Mean knowledge scores of nurses from General and Cancer hospitals were 14.73 and 16.33, and mean attitude scores were 149.80 and 150.20. Cancer hospital nurses' expertise and attitude correlated significantly. The results show that 86.67% of nurses believe SIM is a valuable source of information and content to assist them better manage oral cancer patients' oral hygiene and nutrition. Conclusions: The study found that cancer hospital nurses had a higher mean knowledge score than general hospital nurses. Thus, knowledge and attitude are linked, and nurses with higher knowledge have a more positive attitude.

Dr K C Yadav Dr k c yadav

L’usage des langues maternelles dans le français chez ahmadou kourouma et maurice bandaman : insécurité dans la littérature francophone

Les études sur la langue française la présente souvent dans des situations où elle est en contact avec les langues africaines. Elle co-apparait avec les langues africaines dans les discours romanesques. Cette co-apparition n’est pas sans conséquences pour les deux langues en contact. Certains linguistes, surtout les sociolinguistes et les didacticiens, parlent d’insécurité linguistique. Ils la lient à toutes les situations linguistiques où deux langues entrent en contact. Ngamassu (2007, p.94) dit dans ce sens que « toute situation de contact des langues est source d’insécurité linguistique, car aucun locuteur/scripteur ne peut maîtriser toutes les variétés ou niveaux d’une langue ». Cette affirmation restreint l’insécurité au locuteur ou au scripteur. Les linguistes ignorent souvent l’impact négatif du contact des langues et s’intéressent à ses conséquences positives. Cet article a porté sur les manifestations de l’insécurité linguistique dans la prose romanesque de Kourouma et Badaman. Il a permis de voir que l’usage des langues maternelles dans le français constituait une menace de disparition et d’abâtardissement de la langue française.

Assanvo

Legitimate-path formation for aodv under black hole attack in manets

Mobile Ad-hoc Network (MANET) owing to their very open characteristics are being very attractive and adaptive. With the openness comes security issues to be dealt. The most usual attack in mobile ad-hoc network is the black-hole attack. It advertises false path as shortest and newest to the destined node. On gathering packets containing data will drop them and does not send it to the destination. This paper proposes an algorithm to overcome such an attack under Ad-hoc On-demand Distance Vector (AODV) routing protocol in MANETs. The proposal aims to detect and avoid black-hole attack by using the parameters of AODV routing protocol in its enhanced form of route recovery. The proposed algorithm has two different scenarios, where first comes the detection then the avoidance. The simulation results are obtained from NS -2 to authenticate the effectiveness of proposed technique in comparison with the existing protocols in the existence of black-hole attack with respect to change in simulation end time and active number of attackers. The implementation is assessed based on delay, delivery ratio, drop, overhead, throughput and packet forwarding ratio. The results obtained from network simulator are mapped to form a dataset, which is then validated on a modelled fuzzy inference system using MatLab software.

Fahmina Taranum Fahmina taranum

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