Background: This study was conducted to determine the level of the public knowledge, attitudes and practices related to common eye diseases in the southern Indian population. Methods: A cross sectional population-based survey used a semi structured questionnaire on awareness, knowledge, attitude and practices related to eye diseases. Stratified multistage cluster random sampling method was used with a sample size of 867 adults >16 years based on, estimated awareness of cataract 70%, assuming an expected rate of 85%, design effect of 1.5, margin of error 4% with 95% confidence interval with 25% from urban areas and 75% from rural areas. A pilot study was conducted to validate the questions used in the main study. SPSS (version 19) used for analysis. Results: A total of 782/867 (90.1%) subjects participated in the survey, with females 47.4%. Awareness of major eye diseases for cataract 81.5%, glaucoma 47.8%, refractive error 74.3%, squint 89.0%, diabetic retinopathy 65.0% and age-related macular degeneration 36.7% respectively. 41.8% subjects reported wearing glasses either for distance, near or for both. Of the 777 subjects only 294 people underwent an eye examination by an ophthalmologist in the last two years (37.8%). 57.5% subjects had knowledge of the nearest eye care facility within five kilometers of their residence. Electronic media were the major source of information on eye health. Conclusions: Though the awareness levels of common eye diseases were quite high, the knowledge of cataract (10.4%) was poor. There is a need to increase the level of awareness for eye diseases like glaucoma and age-related macular degeneration.

Srinivasa reddy pallerla

The objective of the paper is to predict corporate bankruptcy of selected telecom service sector companies. The study ranges for a period of ten years from 2006-2007 to 2015-2016 for three selected telecom service sector. By applying Altman's Z-score model the study analyze the financial position of the companies and suggests the financial components to be concentrated to improve the financial health. Further the study suggests that the companies should regularly estimate Z-score for making strategies to improve their financial position.

Dr. jeyalakshmi p

Industrial waste is one of the most essential sources of contamination in the surface environment. Among different industries, tannery industry releases huge amount of pollutants into the ecosystem. Long term disposal of the tannery wastes has resulted in wide contamination of agricultural land and water sources in different parts of India. An attempt was made to study the diversity status of different microbial organisms in tannery effluent treated samples in Dindugal, Tamil Nadu. It was found that Electrical Conductivity (EC) and heavy metal contents were higher and population density of different beneficial microbes found better. Among different microbes isolated, phosphate solubilizing microbes (PSB) was found maximum which is followed by fungi and actinomycetes. The population density of non-symbiotic and symbiotic nitrogen fixers were found to be low in numbers when compared to other samples screened. Similarly, occurrence and distribution of AM fungal spores were also found low in heavy metal polluted samples as compared to the samples collected from non-polluted outside tannery effluent treatment area. Among different Arbuscular Mycorrhizal (AM) fungi, Glomus species was found to be dominant in the samples collected from outside tannery effluent treatment area as compared to tannery effluent samples.

Dr. saranya devi k

Service quality is a key factor for success in any hotel. Many researchers have conducted studies on service quality, but only a few studies have been conducted on internal service quality (ISQ) in general, and in the hotel industry in particular. Since there is no general agreement among researchers on the measurement of ISQ, many studies have used SERVQUAL instrument to measure the employees’ perceptions of ISQ. The purpose of this study is to explore the influence of ISQ on employee’s job satisfaction in five-star hotels in Jordan. The current study was carried out by measuring the data gathered through a seven-point Likert scale. The quantitative survey method was applied, and therefore the SERVQUAL instrument was used to measure ISQ, and the Job Satisfaction Survey (JSS) was used to measure job satisfaction. Data obtained from a sample of 238 respondents drawn from 14 five-star hotels in Jordan were analysed with the SPSS software based on descriptive statistics. The study’s findings indicated that the ISQ of five-star hotels in Jordan has a significantly positive influence on an employee’s job satisfaction. These findings support the hypothesis that there is a positive relationship between ISQ in the hotel industry and industry employees’ job satisfaction.

Mukhles m. al-ababneh

Vehicular adhoc structures (VANETs) handle the Public Key Infrastructure (PKI) and Certificate Revocation Lists (CRLs) for their security. In any PKI structure, the check of a got message is performed by checking if the check of the sender is joined into the current CRL, Verifying the reliability of the certification and standard for the sender. In this paper, it has been propose a Vehicular Digital Hash Gen show up (VDHG) for VANETs, which replaces the dull CRL checking process by a profitable revoking checking process. The renouncing check process in VDHG uses a Private Key Infrastructure (PKI), where the key used in finding the VDHG is shared particularly between On-Board Units (OBUs). In like manner, VDHG uses a novel probabilistic key stream, which extras with OBUs to trade and revive an issue key. VDHG can on a very basic level lessen the data torment in light of the message declaration deferral pulled back and the standard assistance structures using CRL

Dr h shaheen

Potato starch extraction is a critical process with implications across various industries, including food, pharmaceuticals, and bioplastics. This review explores current techniques, challenges, and future opportunities in potato starch extraction. Traditional methods such as compression or wet grinding, enzymatic processes, and microwave-assisted extraction are examined for their efficiency, advantages, and limitations. The paper emphasizes the importance of quality control measures to ensure the purity and safety of the extracted starch. Critical quality control aspects include raw material inspection, monitoring during processing, purity and composition analysis, and adherence to national and international standards. Innovations in extraction methods, including enzymatic and green solvent extraction, ultrasonic and microwave-assisted techniques, and advancements in nanotechnology and biotechnological approaches, are highlighted as trends driving the industry towards greater sustainability and efficiency. The clean label movement also reflects a consumer-driven shift towards natural, minimally processed ingredients, influencing industry practices and regulatory compliance. The future of potato starch extraction holds significant promise, with the integration of sustainable practices and technological innovations to meet evolving market demands and regulatory standards, underscoring the need for continuous research and development in the field.

Dr. salman ahmed

Formality transfer seeks to adjust text formality without altering its core meaning, which carries substantial implications across diverse domains like machine translation, dialogue systems, and social media content creation. This study provides an extensive overview of formality transfer specifically within Arabic text, an emerging domain within natural language processing. Particularly, we carried out a comprehensive review of literature on text formality transfer, focusing on studies published between July 2010 and April 2024. Our focus lies in treating formality transfer in Arabic as akin to a machine translation task, presenting synthesized insights. Despite advancements in formality transfer for English and other languages, Arabic’s distinct linguistic features present unique challenges and opportunities. Our investigation uncovers several research gaps necessitating future exploration, emphasizing persistent limitations. Moreover, we delve into text formality transfer as a promising avenue for forthcoming research initiatives in the realm of Arabic text processing.

Shadi abudalfa

This study aims to determine the functional literacy acquisition of Alternative Learning System learners and make a sound basis for strategic planning and pedagogical intervention that will help promote and develop the said program. The descriptive-evaluative method of research was used in the study. The descriptive method was used to identify the respondents' profile based on (a) age, (b) gender, (c) civil status, and (d) employment status. The evaluative method was used to determine the respondents' functional literacy acquisition in (a) communication skills, (b) scientific and critical thinking skills, (c) mathematical and problem solving skills, (d) life and career skills, (e) understanding the self and society, and (f) digital citizenship (formerly digital literacy). Frequency Count and Percentage Technique was used to describe the functional literacy acquisition of the respondents. Meanwhile, a modified survey questionnaire based on the functional literacy, education and mass media survey ("National Profile of Adult Literacy and Numeracy Skills," 2004, p. 91) was used as the primary tool to gather the data. The respondents in this study were the students enrolled in ALS-Sipocot (North and South District), the school year 2019-2020. Due to COVID restrictions, other ALS learners from other municipalities were not covered as part of the study. Findings revealed that ALS learners do not yet manifest the complete acquisition of functional literacy needed to face the globalized world's challenges because their attainment of the required functional literacy skills is generally low. Moreover, the study disclosed that sex, age, civil status, and employment status affect the acquisition of functional literacy skills among ALS learners in Sipocot, Camarines Sur. Based on the results, the researcher developed an extension activity to help the ALS learners improve their functional literacy, particularly in the digital citizenship area, where they got the lowest score.

Darrel ocampo

Lightweight materials are increasingly being used in engineering applications today. Composites are replacing traditional metallic materials in a variety of sectors, including aerospace, defence, and aircraft production, where there is a demand for structural materials with high strength-to-weight and stiffness-to-weight ratios. Natural fibre composites are also increasingly used in place of synthetic fibre composites in a variety of technical fields due to their affordability and environmental friendliness. In this particular study, Kevlar (Aramid fibres) is combined with other materials to improve the mechanical characteristics and impact resistance of composites. The only material that costs more than Kevlar is carbon fibres. The goal is to maximize mechanical qualities while utilizing the fewest amounts of pricey Kevlar fibres possible. The hand layup technique was used to create the hybrid composites, which included both natural and Aramid fibres. The performance of various mechanical properties was then assessed. In addition, a morphological examination was done to look at the interior structure of the composite materials that were examined. The results show that the hybrid composite, with or without the addition of nanoparticles, demonstrates great strength with little reliance on Kevlar fibres.

Boopathy govindarajan

In health care delivery systems, if you are not part of the solution, then you must be part of the problem. Over the last few decades, clinical pharmacy encourages pharmacists and pharmacy support staff to move their focus from product-oriented role towards new direct engagement with patients, to make the most of the benefits that patients obtain from the medicine they take, or the problems they encounter with their medicines use. In the USA, pharmacists’ participation in physicians ward rounds was shown to reduce adverse drug events by 78% and 66% in general medical and intensive care settings [1. 2]. A study covering 1 029 US hospitals indicated that centrally based and patient-specific clinical pharmacy services are associated with reduced mortality rates [3]. The services involved were medicine information, clinical research performed by pharmacists, active pharmacist participation in resuscitation teams and pharmacists undertaking admission medication histories. New pharmacists’ roles in healthcare systems around the globe have moved and developed significantly over the past few years, particularly with expansion of the scope of practice which allows pharmacists to focus on the clinical aspects of direct patient care [4, 5]. Pharmacists are drug therapy experts of health care team. Therefore, pharmacists, today, are the arbiters of effective and safe use of medicines. Medication therapy management is one of the major areas in which physicians more and more rely on pharmacists to benefit their patients.

Mediterranean journal of pharmacy and pharmaceutical sciences

Nature provides drugs in the form of medicinal plants to cure all ailments of mankind with fewer side effects. These medicinal plants can cause some serious damaging effects on the vital organs of the body too; there is a need of toxicity studies to provide their safe use both in human and animals. The present study reports the acute systemic toxicity of methanolic extracts of leaves of Adenanthera pavonina L., Peltophorum roxburghii Deneger., Prosopis cineraria Druce and Prosopis juliflora DC., (Mimosaceae) in swiss albino mice to explore their suitable doses for pharmacological screening. Observations were made immediately and after 1/2, 1, 4, 24 and 48hours of intraperitoneal drug administration. Adenanthera pavonina extract at the dose of 150 mg/kg body weight is considered to be safe. Whereas remaining extracts of investigated plants are relatively safe at the dose of 100 mg/kg body weight.

Dr. salman ahmed

ABSTRACT The 2006 International Telecommunication Union (ITU) Radio World Conference treaty concluded that all countries should migrate from analogue to digital terrestrial television by June 2015, starting with region one countries, comprising Africa, Europe, the Middle East and the Republic of Iran (Agona & Otim, 2012). The purpose of this research was to explore the technology adoption model (TAM) to address challenges associated with digital terrestrial television migration, and analyse the readiness of South Africa to migrate. A quantitative research was conducted in order to determine the relationship between dependent and independent variables. Digital television offers many benefits for broadcasters, network operators, spectrum regulators, and consumers. In most countries, the transition was slower than expected, even though most European countries managed to migrate. The digital migration is not an easy transition and analogue switch-off can also be much more difficult. Studies have shown that analogue switch off (ASO) needs to be carefully planned and well budgeted for, and it also needs a good publicity campaign which must involve all relevant stakeholders, such as broadcasters, viewers, manufacturers, network operators, manufacturers and retailers. Even though studies conducted previously identified obstacles of digital migration to include; a) lack of awareness b) lack of information, c) influence of politics and d) influence of corruption.

Luyolo mahlangabeza

Objective: To explore unusual association between Turner Syndrome (TS) and Hypopituitarism in a Tunisian cohort. Methods: We reported 6 patients with TS associated to Hypopituitarism, including three familial cases except the fourth sister who showed only a TS phenotype. Biochemical analysis, resonance magnetic imaging and cytogenetic analyses were performed. Results: The average age of our patients was 17.2 years (11-31 years). They were all referred for short stature and pubertal delay, except for the fourth sister who presented spontaneous puberty with the integrity of the pituitary axis and the presence of an X ring chromosome. Karyotype analysis showed monosomy in 3 cases and a mosaic TS in the 3 remaining cases, including one patient with abnormal X chromosome structure. Somatotropic and corticotropic deficiencies were confirmed in 2 sporadic cases while the gonadotropic and thyrotropic axes were spared. In contrast; familial cases were consistently affected by the integrity of the corticotropic axis. MRI showed pituitary hypoplasia in all familial cases and pituitary stalk interruption syndrome in only one sporadic case. No correlation was found between the chromosome formula and the anterior pituitary involvement. Conclusion: Co-segregation of congenital Hypopituitarism with pituitary hypoplasia and X chromosome aberrations could imply a molecular anomaly of transcription factors responsible for the differentiation and development of pituitary cells such as PROP1, POUF1, Hesx1, Lhx3, Lhx4. The etiopathogenic link between X chromosome abnormalities and the occurrence of Hypopituitarism remains unclear; however, the progress of molecular biology may clarify the interrelation between transcription factors and sex chromosome segregation abnormalities.

Mariam moalla

Natural products are a vital source of therapeutic agents due to their diverse chemical structures and wide range of biological activities. With the advancement of computational technologies, natural product databases have become essential tools in drug discovery, offering organized access to chemical structures, biological properties, and biosynthetic information. These databases support various stages of drug development, from target identification to lead optimization. This review outlines the essential features of Natural Products Databases and introduces the framework for the first Libyan Natural Products Database, a project designed to harness Libya’s unique biodiversity. This foundational work involves a detailed review of existing natural product databases to identify their core components, data architectures, and user interface designs. While acknowledging challenges such as data standardization, limited resources, and long-term sustainability, the creation of the Libyan Natural Products Database is expected to enhance local scientific capacity and contribute meaningfully to the global drug discovery landscape. This positions the Libyan Natural Products Database to play a foundational role in advancing pharmaceutical research and drug discovery.

Mediterranean journal of pharmacy and pharmaceutical sciences

Background: Pre-eclampsia remains a significant contributor to maternal and perinatal morbidity and mortality. Research into changes associated with the disease offers some hope into identifying predictive and prognostic factors. In recent times, serum leptin has attracted interest as a possible marker for the disease. The aim of this study was to determine and compare the serum leptin levels in normotensive and pre-eclamptic pregnant women attending antenatal clinic at the Delta State University Teaching Hospital, Oghara, Delta State, Nigeria. Methods: This was a prospective case-control study design at the Delta State University Teaching Hospital, Oghara, Nigeria in which sixty three pregnant women who received antenatal care and developed pre-eclampsia were recruited into the study. For each selected pre-eclamptic, a matched normotensive was selected as control. Serum leptin level was measured by radioimmunoassay (RIA) ELISA. Results: There was a statistically significant difference in mean serum leptin levels between the normotensive and pre-eclamptic pregnant patients 15.11±4.81 ng/dl vs 38.98±8.66 ng/dl; p<0.001. Furthermore, there was a statistically significant difference in mean leptin levels between mild and severe pre-eclampsia; 16.49±8.22 ng/dl vs 39.03±8.58 ng/dl;p<0.001.Conclusion: This study revealed an association between serum leptin level and pre-eclampsia. Serum leptin may be a potential marker for pre-eclampsia and deserves further investigation.

Karishma

Production process in the manufacturing industries has proven wasteful of the resources in the production process over time. integrating of lean principles in the manufacturing activities has brought notable success in a complex and slow production process in an industry. This study aims at integrating of lean principles to a product development process to eliminate break down cases as it makes the process easy as well as speeding up the product development in an automotive industry. Three major phases are applied in product development namely; the early concept phase, middle core design and the launch phase. An exceptional definition of products development of lean principles are applied to come up with an analysis framework. Through interviews, observations, documentation and experience barriers that causes large number of wastes can be established. Lean principles will then be applied to eliminate such causes in the product development and then derive conclusion that shows the industry the process of lean in product development in the entire process

Levi p. cheworei

The choice of the study design is a major determinant of scientific quality and clinical value of a research study. To select an appropriate study design is a perplex task for novice as well as veterans in research. AYUSH systems of medicines have evidence database showing the effectiveness in a wide range of clinical conditions, yet improving the quality of trials by well- designed studies is indispensable to demonstrate widespread utility on more scientific grounds. This article describes the structured classification of research designs done on the basis of a selective literature search concerning medical research. The study design and type that can best answer the particular research question at hand must be determined not only on a scientific basis, but also in view of the available resources, ethical issues and practical feasibility of study.

Dr deepthi gilla

Family businesses must harness the full potential of their human resources and maintain employee loyalty to achieve the companies’ objectives effectively. This study examines the influence of transformational leadership on employee commitment through work-life balance and workplace social support. The research was conducted from August to December 2023 using an online questionnaire distributed to employees in a family firm in Medan, Indonesia. The data were then analyzed using PLS-SEM. The results show that transformational leadership significantly effects employee commitment, work-life balance, and workplace social support. However, although workplace social support mediates the relationship between transformational leadership and employee commitment, work-life balance fails to do so. It was also found that work-life balance has no direct influence on employee commitment. Using an IPMA analysis, this study highlights the importance of transformational leadership and workplace social support in the family business environment. Transformational leadership has also been shown to have the best performance and effect on employee commitment. Managers should prioritize these aspects to reduce employees’ stress levels, improve psychological well-being, and increase job satisfaction, leading to a more committed, high-performance workforce.

L

Cryopreservation is a process that preserves intact living cells, tissues or any other biological constructs by cooling and storing the samples to very low temperatures in order to maintain their viability and to save them for future use. At very low temperatures, enzymatic and chemical activities that may cause harm to the biological material are effectively stopped. Cryopreservation methods look to reach very low temperatures without causing further harm caused by the creation of ice crystals during freezing. Cryopreservation human samples for storage including variety of diseases such as cancer, genetic and degenerative disorders and bio-banking. This review aims to describe and highlight dimethyl sulfoxide in cryopreservation. Dimethyl sulfoxide is a non-toxic solvent and is one of the most commonly used pharmaceutical agent with a varied range of pharmacological actions including membrane penetration, anti-inflammatory effects and local analgesia as well as weak bacteriostatic. The main use of dimethyl sulfoxide is a vehicle for some drugs to enhancing the action of the drug and helping penetration of other drugs into the skin. However, dimethyl sulfoxide has been the cryopreservative agent of choice in situation to its exceptional performance in mitigating freezing-related damages. It is frequently used in cell banking applications as a cryoprotectant. When added to media, it prevents intracellular and extracellular crystals from forming in cells during the freezing process. There has been a concern over the toxicity of dimethyl sulfoxide and its potential side effects in different highly concentration after administration to patients. Therefore, there has been growing demand for robust dimethyl sulfoxide for cryopreservation method that can improve safety and maintain potency and efficacy

Mediterranean journal of pharmacy and pharmaceutical sciences

Forecasting methods from averaging regression analysis lines, reversed and direct lines. With both lines intercepting laid the turning points in direction of original line. The average regression method.

Dr abdul rahim wong