Antiurolithiatic plants: formulations used in different countries and cultures

: About 12% of the world population is affected by different forms of urolithiasis, the recurrence rate of which is 47-60% in females and 70-80% in males. According to WHO, 75% of people rely on traditional medicines to prevent and cure different ailments. Similarly, the majority of the world population uses several plants to treat problems related to the urinary tract system, of which urolithiasis is the primary cause. The review aims to collect data on the plants used in different parts of the world and cultures against urolithiasis, including their parts, mode of preparation, dosage, and administration. A literature review was conducted for traditionally used antiurolithiatic plants. The articles mentioning plant, parts, mode of preparation, dose and route of administration were selected. This information was extracted to compose Mono and Polyherbal antiurolithiatic formulations used in Appalachia (a region in the Eastern United States), Canada, India, Iran, Israel, Italy, Jordan, Latin America, Pakistan, Turkey and Yemen. The review provides essential data about plants used as antiurolithiatic in different parts of the world. The information is not only useful for ordinary people but also for the scientific community to carry out further phytochemical, pharmacological and toxicological studies for discovering new, effective, safer molecules against urolithiasis.

Dr. Salman Ahmed Dr. salman ahmed

New dimension in higher education in india

Higher Education has an important role in the task of rebuilding a nation and it pavCes the way for overall development of a nation. The twentieth century has witnessed several revolutions like Green revolution, White revolution, I.T revolution, so on and so forth, taking human civilization to new heights. At the start of 21st century, we gave a lot of importance given to higher education. Every country realized the value of higher education and the benefits that accrue from it. “The social demands for higher education continue to increase. The inabilities of the state to support this growing demand result in new financing arrangements for higher education. The recent reforms in this area could be broadly divided into two categories: the privatization of public institutions and the establishment of private institutions of higher education. Privatization implies the application of market principles in the operation of public institutions, while ownership rests within the public domain. Promotion of the private sector implies the growth and expansion of the non-state sector in higher education, and very often this sector does not rely on state funding for its growth and expansion. Both of these measures have paved the way for market operations in higher education

Dr Gedam Kamalakar Dr gedam kamalakar

A lightweight deep learning framework using resource-efficient batch normalization for sarcasm detection

Communication is not always direct; it often involves nuanced elements like humor, irony, and sarcasm. This study introduces a novel two-level approach for sarcasm detection, leveraging Convolutional Neural Networks (CNNs). Convolutional neural networks (CNNs) are crucial for many deep learning applications, yet their deployment on IoT devices is challenged by resource constraints and the need for low latency, particularly in on-device training. Traditional methods of deploying large CNN models on these devices often lead to suboptimal performance and increased energy consumption. To address this, our paper proposes an energy-efficient CNN design by optimising batch normalisation operations. Batch normalisation is vital for deep learning, aiding in faster convergence and stabilising gradient flow, but there has been limited research on creating energy-efficient and lightweight CNNs with optimised batch normalisation. This study proposes a 3R (reduce, reuse, recycle) optimisation technique for batch normalization. This technique introduces an energy-efficient CNN architecture. We investigate the use of batch normalization optimization to streamline memory usage and computational complexity, aiming to uphold or improve model performance on CPU-based systems. Additionally, we evaluate its effectiveness across diverse datasets, focusing on energy efficiency and adaptability in different settings. Furthermore, we analyze how batch normalization influences the performance and effectiveness of activation functions and pooling layers in neural network designs. Our results highlight batch normalization's ability to enhance computational efficiency, particularly on devices with limited resources.

Jiby Mariya Jose Jiby mariya jose

Classification framework for medical diagnosis of brain tumor with an effective hybrid transfer learning model

Brain tumors (BTs) are deadly diseases that can strike people of every age, all over the world. Every year, thousands of people die of brain tumors. Brain-related diagnoses require caution, and even the smallest error in diagnosis can have negative repercussions. Medical errors in brain tumor diagnosis are common and frequently result in higher patient mortality rates. Magnetic resonance imaging (MRI) is widely used for tumor evaluation and detection. However, MRI generates large amounts of data, making manual segmentation difficult and laborious work, limiting the use of accurate measurements in clinical practice. As a result, automated and dependable segmentation methods are required. Automatic segmentation and early detection of brain tumors are difficult tasks in computer vision due to their high spatial and structural variability. Therefore, early diagnosis or detection and treatment are critical. Various traditional Machine learning (ML) techniques have been used to detect various types of brain tumors. The main issue with these models is that the features were manually extracted. To address the aforementioned insightful issues, this paper presents a hybrid deep transfer learning (GN-AlexNet) model of BT tri-classification (pituitary, meningioma, and glioma). The proposed model combines GoogleNet architecture with the AlexNet model by removing the five layers of GoogleNet and adding ten layers of the AlexNet model, which extracts features and classifies them automatically. On the same CE-MRI dataset, the proposed model was compared to transfer learning techniques (VGG-16, AlexNet, SqeezNet, ResNet, and MobileNet-V2) and ML/DL. The proposed model outperformed the current methods in terms of accuracy and sensitivity (accuracy of 99.51% and sensitivity of 98.90%).

Mehdhar S. A. M. Al-Gaashani Mehdhar s. a. m. al-gaashani

A study on biocontrol and plant growth promoting efficacy of azadirachta indica (neem) leaf endophytic bacteria

Background and Objective: Endophytic bacteria can protect host plants by producing secondary metabolites and also improve host plant growth by various mechanisms. This unique character makes a special role in, using endophytic bacteria in sustainable agriculture. The study aims to isolate endophytic bacteria from Azadirachta indica (neem) leaf and screened for their biocontrol and plant growth-promoting properties. Materials and Methods: Totally 13 endophytic bacteria isolated from neem leaf and it was tested for their in-vitro antifungal activities against Rhizoctonia solani. A total of 3 isolates (N1B, N4B and N5B) were selected on the broad antifungal activity (50%, 56%, 75% mycelial inhibition). Among different solvents used for the extraction of secondary metabolites from endophytic bacteria, only ethyl acetate extract of N5B showed maximum zone of inhibition in well diffusion method against fungal pathogen. Results: The GC-MS analysis of ethyl acetate extracts of N5B exhibited 14 compounds with antifungal activity, such as Dimethoxyglycerol docosyl ether, Pentadecanoic acid, Oleic acid etc. Selected 3 endophytic isolates were identified up to molecular level using 16S rRNA sequencing and it was identified as Bacillus haynesii, Stenotrophomonas maltophilia and Pseudomonas aeruginosa. The identified isolates were used for nursery experiments based on their strong in-vitro antifungal and PGP activities such as P, K, and Zn solubilization, N fixation, IAA, HCN and EPS production. Conclusion: The tested bacterial isolates significantly decreased disease severity in rice, infected with R. solani and increased plant biomass when compared with un-inoculated control. Our findings suggested above mentioned 3 bacterial species may be promising candidates as a biocontrol agent to confer resistance to sheath blight disease of rice.

Dr. SARANYA DEVI K Dr. saranya devi k

Information systems and technology in business

Management information systems are computer systems within an organisation that incorporate both hardware and software operations. It involves using business processes, people, and technology to collect, record, process, and store essential data that is significant to decision-making processes (Hartanto and Asmuni, 2017, 11). Management information systems are also used to coordinate, analyse, control, and visualise crucial organisational information. The ultimate goal of using MIS within the corporate environment is to increase value creation and profit earnings for businesses.

Zamzam Abdelazim Zamzam abdelazim

Screening and selection of potential beneficial rhizosphere fungi from medicinally important plant species in tamil nadu, india,

The problem of chemical fertilizers and pesticides can be solved by the action of plant growth promoting fungi (PGPF). The indigenous fungal isolates obtained from the rhizosphere soil can be used as they are said to solubilize the insoluble zinc, phosphorous, potassium etc. They are known to control the different fungal pathogens and thus promoting the plant growth and health. In the present study, attempt was made to isolate soil beneficial fungi from the rhizosphere soil samples of important medicinal plants such as Aegle marmelos, Azardirachta indica and Citrus limon. A total of 22 fungal isolates was isolated and screened for their efficacy on phosphate and zinc solubilization and antagonistic potential against selected plant pathogenic fungi under in vitro condition and the isolates were identified up to species level.

Dr. SARANYA DEVI K Dr. saranya devi k

Ecological niche modeling to assessment of potential distribution of neodiprion abietis (harris, 1841) (insecta, hymenoptera, diprionidae) in eurasia

In the article first assesses the potential distribution in Eurasia of Neodiprion abietis (Harris, 1841) first time assessed. The species id a widely distributed in North America fir and spruce defoliator, intercepted in 2016 in the Netherlands. Analysis of the literature data on the known distribution and host plants of the species is given. Insufficient data for ecological modeling is shown, which causes a high degree of uncertainty in assessment of potential range. The results of modeling the potential range of the species using several algorithms are presented. The reliability of the obtained models and the importance of bio-climatic environmental variables for species distribution are assessed.

Svedbergopen

Firearms in mughal india

During the 16th century, firearms played a transformative role in Indian warfare, considerably enhancing the effectiveness of the Mughal army. The introduction of muskets and artillery by Babur in 1526 revolutionized military strategies, giving the Mughals a decisive advantage in battles and sieges. The Mughal army’s structure, particularly under Akbar’s Mansabdari system, centralized control and ensured a loyal, efficient military force. This technological and organizational superiority enabled the Mughals to consolidate power over diverse regions through a combination of military might and diplomacy. By the 17th century, there was a significant change in rebellions as firearms started being used by peasants. This shift in weaponry fundamentally altered the nature of these uprisings, empowering the peasantry in new ways to resist authority. Multiethnic regional powers also recognized the importance of firearms, acquiring them from the Mughals or Europeans, and employing them effectively in battles. In the mid-18th century, the Marathas and later the Mysore Sultanate took a notable step by establishing arms factories and engaging European experts to produce advanced firearms. This marked a departure from the past, where regional powers typically relied on the Mughals or European companies for firearm procurement. This shift toward domestic arms production signaled a move toward greater self-sufficiency and the development of advanced firepower. By the 18th century, the Mughal Empire was in decline, and multiethnic regional powers and European colonial forces, equipped with advanced firearms, challenged and eventually overshadowed Mughal dominance.

Bidyut Patar Bidyut patar

Chemical analysis and analgesic activity of methanol extract of crinium jagus bulb in balb/c mice

Crinum jagus, family- Amaryllidaceae, commonly called river lily is an important medicinal plant used in the treatment of cough. It is an anti-venom agent used among the rural people in south-western Nigeria. The research is aimed to investigate the phytochemical constituents and analgesic activity of Cinium jagus bulb in BALB/c mice. The bulb was extracted with methanol in a soxhlet extractor apparatus. Phytochemical screening was performed according to standard methods. Alkaloid fraction was obtained using separation by extraction and characterized by infra-red (I.R) analysis. Acute toxicity test was done before analgesic activity was determined in BALB/c albino mice using the hot plate model. The result indicated the presence of some bioactive constituents like alkaloids, terpenoids and saponin. I.R bands were observed at 1064.74 cm 1 (C-O) stretch of alcohol; 1415.80 cm-1 (C-H) bend of alkyl groups and 1639.55 cm-1 (N-H) stretch of amine among others. The extract significantly increased the mean latency time of mice on the hot plate when compared with control with 100 mg/kg at 120 minutes. This study indicates that the Crinum Jagus bulb possesses analgesic potential.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

A retrospective cohort study of decompressive techniques for cubital tunnel syndrome: in situ decompression versus ulnar nerve transposition

Background: Cubital tunnel syndrome (CuTS) is the second most common nerve entrapment syndrome of the upper extremity after carpal tunnel syndrome. In situ decompression (ISD) and ulnar nerve transposition (UNT) are the major surgery methods in practice for the treatment of CuTS. However, controversies exist over the efficacy and safety of these methods. Aim: The objective of the study was to compare the short- and long-term clinical outcomes in patients treated with ISD and UNT surgery. Method: This was a retrospective study comprising 56 patients who underwent either ISD or UNT at Naresuan University Hospital between January 2013 and December 2022. Data on age, sex, hand involved, duration of the surgery, duration of the symptoms including the clinical outcomes such as elbow range of motion (ROM), quick disabilities of the arm, shoulder, and hand (QuickDASH), McGowan grade (MGG), Visual Analog Scale (VAS) for pain scores, motor and sensory conduction velocity (MCV1, MCV2, and SCV), and Tinel's sign were collected during the two-week, one-month, three-month, and six-month follow-ups post-surgery. Results: Of the 56 patients in the study, 62.5% were female. The number of patients aged <60 years was higher in both groups. The mean age of patients in the ISD group was 49.07±6.13 years, while in the UNT group, it was 51.5±7.04 years. After one month, 53.57% and 32.14% of the patients recovered to MGG 1 in the ISD and UNT groups, respectively. The majority of the patients had MGG 1 six months after the surgery. The QuickDASH score and pain scores of the patients improved during all follow-ups, but no statistical significance was revealed when the two techniques were compared. Conclusion: The study found that both the ISD and UNT were efficient and safe in treating CuTS. Further study with the inclusion of parameters such as revision surgery and complications would be vital.

Saran malisorn Saran malisorn

A comprehensive review of macrotyloma uniflorum: nutritional composition, health benefits, and potential applications.

 ABSTRACT Macrotyloma uniflorum, commonly known as horse gram, is an underused pulse that holds great potential as a supply of nutrition and functional compounds. This review paper aims to provide a comprehensive overview of the nutritional composition, Pharmacological activities, health benefits, and potential applications of Macrotyloma uniflorum. Horsegram has a high amount of protein, dietary fibre, and a variety of vital minerals and vitamins that make up its nutritional profile. Horsegram also has a high content of antioxidants, flavonoids, and phenolic compounds, all of which contribute to its potential health advantages. Horsegram intake has the potential to help manage a number of chronic conditions, including diabetes, obesity, cardiovascular problems, and gastrointestinal disorders, according to many studies. The review investigates the possible health advantages of Macrotyloma uniflorum, emphasising its function in controlling blood sugar, managing weight, lowering cholesterol, and antioxidant activity. Horse gram's medicinal potential is further increased by the presence of bioactive substances that include anti-inflammatory, antibacterial, diuretic, antiobesity, analgesic, anaphylactic action, and anticancer activities. In conclusion, this review paper presents a comprehensive evaluation of Macrotyloma uniflorum, highlighting its nutritional composition, health benefits, and potential applications. The findings underscore the significance of horse gram as a valuable functional food ingredient and encourage further additional investigation of its therapeutic properties for human health and well-being.

Asawari Mansabdar Asawari mansabdar

Assessment of knowledge and awareness of community pharmacist toward epilepsy

Community pharmacist plays an essential role in educating the epileptic patients about their disease and medications. Improving the patient’s awareness may lead to improve their compliance and decrease drug-drug interaction and ultimately improve their quality of life. Pharmacist can detect the emergence of health problems and can help prevent progression of comorbidities. Considering the complexity of treating epilepsy and the lack of information about pharmacists’ contributions to epilepsy management, pharmacist performed pharmaceutical counselling, pharmaco-therapeutic follow-up and systematic measurement and evaluation of findings and increase medication adherence of patient with epilepsy. This study was aimed to assess the community pharmacist's knowledge about epilepsy and their treatment by antiepileptic drugs in Libya. The design of the study is a cross sectional study. The knowledge was collected through a questionnaire which included 35 questions divided into three sections: demographic data, general information about epilepsy and information about epilepsy and antiepileptic drugs. The questionnaire was prepared and validated by consultant training in Ali Omer Asker Hospital in Tripoli for two months. The findings indicate that over 200 patients are altered viewed, of whom, only epileptic patients were observed. The majority of the participants were female, qualification degree BSc and years of experience from one to five years. Unfortunately, some of the participants (40.0%) had poor knowledge and about 60.0% of them had good knowledge. This study indicates that the importance of community pharmacist in Libya requires more improvement to achieve the existing function and that the impact of continuous study of everything related to diseases and medicines is important to obtain a qualified pharmacist who can become an effective agent for a change.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

A study of beliefs of teacher educators about relationship between teaching and research

The purpose of this study is to explore the belief of teacher educators about the relationship between teaching and research. Keeping in view the role of the teacher educators, a survey was done. The beliefs of teacher educators were explored with the help of an opinionaire. The collected data were analyzed through qualitative method of analysis. It was found that the secondary teacher educators were positive about the need of research with a little dilemma between teaching and research.

Rupal Mankad Rupal mankad

Laboratory findings of libyan patients with covid-19 in intensive care unit

The 2019 coronavirus disease (COVID-19) was declared by the World Health Organization as a pandemic on 11th March, 2020 which spread rapidly all over the world. COVID-19 disease has different clinical presentations, ranging from asymptomatic to severe symptoms. Laboratory findings are important in determining which therapeutic strategies to seek and to identify severe cases initially. In this study, we compared the results of C-reactive protein, D-dimer, blood electrolytes and mean corpuscular hemoglobin concentration between survivors and non-survivors of 22 Libyan patients with COVID-19 present in the intensive care unit at Maitika Isolation Center (Tripoli, Libya) in the period of January to June 2021. We could not detect any significant difference in C-reactive protein between survivors and non-survivors but a significant difference in D-dimer level was observed. Non-survivor COVID-19 patients have a higher level of D-dimer. Moreover, a statistical significant difference in chloride and sodium levels but not in potassium level were detected. A marked lower of mean corpuscular hemoglobin in non-survivor than survivor COVID-19 patients was shown. Thus, these parameters could act as biomarkers for COVID-19 patients.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Radial nerve palsy secondary to congenital constriction ring syndrome in a neonate: a case report and literature review

Congenital constriction band syndrome (CBS) is a rare condition characterized by either partial or complete circular constrictions around limbs or digits. Possible consequences include acrosyndactyly of the digits, terminal amputations, and localized swelling with digital edema distal to the constrictions. Occasionally, a constriction band may lead to injury of a peripheral nerve. We report a case of CBS in a newborn presenting with radial nerve palsy caused by a constriction band at the level of the arm. Surgical release of the congenital constriction band was performed at 1 month of age, including neurolysis of the radial nerve. As a result, the nerve was decompressed, and hand function was restored. Given the rarity of radial nerve palsy as a complication of congenital constriction bands, this case enriches the limited literature by emphasizing the importance of early diagnosis and prompt surgical intervention to optimize functional outcomes. It also highlights the need for increased clinical vigilance and provides practical insights into managing isolated radial nerve palsies.

Karishma Karishma

Availability of disaster preparedness and digitization in archives preservation in public libraries in rivers state

This study ascertained availability of disaster preparedness and digitization in archives preservation in public libraries in Rivers state. Two objectives and its corresponding research questions and hypotheses guided this study. The descriptive survey design was adopted for this study. The target population of this study comprised 514 library staff drawn from Rivers state library board and staff from Jubilee library Port Harcourt. The sample size for this study was 399 library staff comprising of 227 staff from Rivers state library board and 172 library staff from Jubilee library Port Harcourt. The sample size was determined by Taro Yamane sample size determination formula while a two-stage sampling technique of stratified and simple random sampling techniques was used to select the sample size. A self-structured questionnaire titled availability of disaster preparedness and digitization in archives preservation questionnaire was used as the instrument for data collection. Face and content validation was ensured by three experts. The instrument yielded reliability coefficients of 0.79 with the use of Cronbach Alpha reliability method. Meanand Standard Deviation was used in answering research questions while z-test was used for the inferential statistics. The findings revealed that disaster preparedness and digitization in the preservation of archives are supported and available in public libraries in Rivers state, Nigeria. Based on the findings, it can be concluded that there are significant differences in the responses of Rivers state library board staff and Jubilee library Port Harcourt staff on the terms of the availability of the disaster preparedness and digitization in archive preservation in the public libraries. It was therefore recommended that more librarians should be employed by the Rivers state government so as to make the process of archive preservation in the State’s public libraries through disaster preparedness and digitization less rigorous and efficient.

FXintegrity Publishing Fxintegrity publishing

Innovative ideas to sustain in covid-19 lockdown-a case study

The covid-19 lockdown has made many people of the middle- and lower-income class think and reinvent themselves to sustain in this crisis. It was difficult for lower- and middle-income class people to adjust to the situation of lockdown. Government and private institutions have reduced the salaries to the employees in view of the 40-day lockdown. Lockdown has made people rethink and reinvent to sustain in this tough time. People have modified their work and style of working to acclimatize to lockdown. Work from home in the software industry, telemedicine and video consulting in the healthcare industry, online classes and tutoring in the education system, farm to house vegetable delivery system in the agricultural sector, the surge in online pharmacy business, MSME- handmade mask industry, MedTech zones for demand in medical equipment. Private sector isolation centres in partnership with reputed hospitals. We throw light on some of these innovative ideas that could change the present and future of living in difficult times. innovative ideas for students during lockdown

Kamal Singh Kamal singh

Secured data transmission in vanet using vehicular digital hash gen model

Vehicular adhoc structures (VANETs) handle the Public Key Infrastructure (PKI) and Certificate Revocation Lists (CRLs) for their security. In any PKI structure, the check of a got message is performed by checking if the check of the sender is joined into the current CRL, Verifying the reliability of the certification and standard for the sender. In this paper, it has been propose a Vehicular Digital Hash Gen show up (VDHG) for VANETs, which replaces the dull CRL checking process by a profitable revoking checking process. The renouncing check process in VDHG uses a Private Key Infrastructure (PKI), where the key used in finding the VDHG is shared particularly between On-Board Units (OBUs). In like manner, VDHG uses a novel probabilistic key stream, which extras with OBUs to trade and revive an issue key. VDHG can on a very basic level lessen the data torment in light of the message declaration deferral pulled back and the standard assistance structures using CRL

Dr H Shaheen Dr h shaheen

Post-merger profitability of selected banks in india

The present study aims to shed some light on the gains from consolidation exercise in terms of profitability of banks. Through the application of paired t-test, we arrived at the result that the consolidation of banks did improve the profitability of banks in India. The increase in profitability of banks under study is due to an increase in employee turnover and the subsequent reduction in operating expenses. Merger and acquisition programmes in Indian banks cannot be regarded as a false step if the benefits of it accrue to all stakeholders.

Akhil Antony Akhil antony

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