The genus Caesalpinia belongs to the family Caesalpiniaceae and includes 280 species distributed in tropic and subtropical regions of the world. Historically, species of the genus Caesalpinia have been used to treat a wide range of ailments, such as malaria, ascariasis, dysentery, fever, rheumatism, and influenza. Phytochemical works led to the isolation of triterpenoids, diterpenes, flavonoids, steroids and phenolic compounds. Pharmacological studies have shown that the extracts and compounds isolated from this genus exhibited anticancer, anti-inflammatory, anti-malarial, antipyretic, anti-microbial, anti-rheumatic, antiulcer and anti-diabetic activities. Therefore, this review aims to provide a comprehensive overview of the genus Caesalpinia's ethnopharmacology, phytochemistry and pharmacology.
Wireless Sensor Networks (WSNs) received enormous attention in recent years due to its phenomenal ability of implementation in various fields. WSNs consist of a large number of small sensor nodes. These nodes are very cheap in terms of cost. In military operations, there is always a threat of being attacked by enemies. So, the use of these cheap sensor nodes will help to reduce the loss. In this project, the security of data transmission in WSNs for military applications is analyzed. It discusses the available scenarios of using sensor nodes in the military uses. The aim is to present a better deployment of sensor nodes for military purposes with the help of cryptographic techniques. This project will try to identify different areas in which we can reduce the damage in case of militant’s attack or enemy’s outbreak using an intelligent deployment of nodes. It is proposed to use the WSNs in battlefield surveillance to closely monitor the critical areas and borders to obtain information about enemy activity in that area. Hence, militant’s will gather information quickly which will result in quick response. Border monitoring is an essential component of military surveillance to prevent enemy’s intrusion. Here the proposed work provides security using several techniques to encrypt and decrypt the data in WSNs. Elliptic Curve cryptography involves Attribute based encryption which is more complicate to hack. As well as skipjack is used to create digital signature to avoid unauthorized users.
Critical race theory (CRT) is an intellectual movement that seeks to understand how white supremacy as a legal, cultural, and political condition is reproduced and maintained, primarily in the US context. While CRT is part of a much longer research tradition investigating race and racism, which includes such key fgures as W. E. B. Du Bois, Frantz Fanon, Angela Davis, Audre Lorde, Gloria Anzaldúa, Cherríe Moraga, and many more, CRT distinguishes itself as an approach that originated within legal studies (in part building from and responding to critical legal studies); aims to be a vehicle for social and political change; has been adopted interdisciplinarily across many fields, including perhaps most notably education; and, in certain contexts, has come to be the umbrella term for studies of race and racism generally. CRT originated as an extension and critique of critical legal studies (CLS). It was also an outgrowth of Marxist critical theory that challenged the rationality, impartiality, and purpose of the legal system. According to the tenets of both CRT and CLS, the legal system is a political and ideological institution that, in part, rationalizes and justifies the existence of the state. Te legal system also requires mastery of an arcane and intentionally inaccessible vocabulary and a set of knowledge and power processes that limit ordinary people’s access to it. Te arbiters of law pretend to rely on reason but actually rely on subjective, politically motivated, culturally biased, and quasi-religious rationale for making and enforcing their decisions. CRT maintains the critique of legalistic thinking found in critical legal studies, but then adds a framework for understanding white supremacy as an immutable fact of a neocolonial state, as well as a praxis for changing it. What separates CRT from other forms of racial critique is that, “Unlike most of the earlier genres of race cholarship, critical race scholarship does not treat race as an independent variable; rather, it regards race as a site of struggle” (Orbe & Allen, 2008, p. 209).
In the teaching and learning process, teachers are required to be able to carry out their role to the fullest as a motivator and initiator in an effort to maintain and at the same time increase the enthusiasm of students to learn. Especially in the Covid-19 pandemic situation which requires educational institutions to carry out online learning. This study aims to discuss the teacher's role as a motivator and the teacher's role as an initiator in improving the quality of student learning in online learning at Madrasah Ibtidaiyah Ma'arif Condro Jember. This research uses qualitative research methods and the type of research is a case study. Data collection techniques using observation, interviews and documentation. The validity of the data using source triangulation and technical triangulation. Meanwhile, data analysis uses data condensation, data presentation and verification/conclusion. The results of this study indicate: 1) The teacher's role as a motivator in improving the quality of learning in online learning, namely: providing opportunities for students to play an active role in learning, providing reinforcement, praise or verbal appreciation, teachers listening to students' concerns and wishes to bond. good relationship between teachers and students. 2) The role of the teacher as an initiator in improving the quality of learning in online learning, namely: utilizing information and communication technology such as Whatsapp, Facebook, Google Meet and Google Form. Dalam proses belajar mengajar, guru dituntut untuk mampu melaksanakan perannya secara maksimal menjadi motivator dan inisiator dalam upaya menjaga dan sekaligus meningkatkan semangat belajar peserta didik. Terlebih dalam situasi pandemi Covid-19 yang menuntut lembaga pendidikan untuk melaksanakan pembelajaran secara Daring. Penelitian ini bertujuan untuk membahas tentang peran guru sebagai motivator dan peran guru sebagai inisiator dalam meningkatan kualitas belajar peserta didik pada pembelajaran daring di Madrasah Ibtidaiyah Ma’arif Condro Jember. Penelitian ini menggunakan metode penelitian kualitatif dan jenis penelitiannya adalah studi kasus. Teknik pengumpulan data menggunakan observasi, wawancara dan dokumentasi. Keabsahan data menggunakan triangulasi sumber dan triangulasi teknik. Sedangkan analisis data menggunakan kondensasi data, penyajian data dan verifikasi/kesimpulan. Hasil penelitian ini menunjukkan: 1) Peran guru sebagai motivator dalam meningkatkan kualitas belajar pada pembelajaran daring yaitu: memberikan kesempatan kepada peserta didik untuk berperan aktif dalam pembelajaran, memberikan penguatan, pujian atau apresiasi secara verbal, guru mendengarkan keresahan dan keinginan peserta didik agar terjalin ikatan yang baik antara guru dan peserta didik. 2) Peran guru sebagai inisiator dalam meningkatkan kualitas belajar pada pembelajaran daring yaitu: memanfaatkan teknologi informasi dan komunikasi seperti Whatsapp, Facebook, Google Meet dan Google Form.
In this report, Tesco PLC's operation and project management have been fully elaborated on. Tesco PLC is a retail organization that deals with retailing and other related activities in insurance service and retail banking (REUTERS, 2020). Tesco is multinational general merchandise and groceries with headquarters at Welwyn Garden City in England. Based on gross revenue rating, Tesco is the third-largest retailer in the world. Tesco was created by Jack Cohen in 1919 in Hackney, London as a set of markets stalls. Tesco developed and expanded very fast in the whole world and above 100 Tesco shops in the entire Facebook. Tesco has segments in ROI and the UK that is; central Europe (Hungary, Slovakia, and the Czech Republic), the Republic of Ireland, and the United Kingdom which do similar activities to those done in Tesco bank in the United Kingdom (Bedford, 2022). Tesco avails different personal banking packages (services and products) that include personal loans, personal current accounts, and credit card receivables. Tesco's businesses are therefore Tesco Hungary, Tesco UK, Tesco Czech Republic, Tesco Slovakia, Tesco Ireland, Dunnhumby, and Tesco Bank.
Avec une très grande intelligence narrative, Leila SLIMANI (2016) déforme les codes du polar et commence par la fin. « Le bébé est mort » la première ligne avec laquelle s’ouvre la scène du meurtre des enfants par la nourrice au visage d’ange. La finesse du détail pertinent et la construction par petites touches des personnages terriblement crédibles caractérisent la plume de Leila SLIMANI. Débarrasser de l’horreur, le lecteur se met à la recherche des failles de cette étrangère de la famille. Rien n’est en trop : dialogues, descriptions, narration haletante et histoire émouvante, ce sont les atouts de la récompense de cette œuvre par le prestigieux prix Goncourt. Inspirer par un fait divers affreux, la romancière livre une photographie d’un ordre social illégal et les forces invisibles qui couvent les relations dans notre société. Leila SLIMANI met en relief une intrigue aux conséquences dramatiques, les contraintes d’une modernité qui s’imposent, infectant la maternité des femmes assoiffées de liberté.
Fueled by the recent advancements in pervasive environment, affluent context aware systems is among the rousing in computing today, including embedded environment, different wireless network technology, electronic communication and so on. Context-Aware Collaborative Filtering using Genetic Algorithm approach resulted in an improved mobile business model by determining optimal similarities between contexts. In this work, we plan to devise a hybrid framework called Multi-distribution Perceptron and Hidden Markov Model to smoothen the mobile networks with different degrees of context- confidence. Initially, Multi-distribution Layer Perceptron Model is designed aiming at improving the precision rate with the aid of Multi-distribution Bayesian Posterior measure. Experimental analysis shows that the M-PHMM framework is able to reduce the computational complexity for obtaining user patterns by 26.05% and improve the precision rate by 18.90% compared to the state-of-the- art works.
The significance of fermentation is gaining more relevance due to the need for better preparation of plants, the desire for better plant constituents, and the aim for the preservation of medicinal plants. Hence, this study sets out to determine and compare the pH, proximate composition, chemical constituents, antioxidant, and antimicrobial effects of 3-day and 7-day fermented seeds of Nigella sativa. The fermentation of the seed was done for 3 and 7 days using 2.5% sugar. The pH of the sample declined from 3.5 to 3.45 during the fermentation. The proximate composition (moisture, ash, lipid, protein, and carbohydrates) was higher for the 3-day fermented sample while fiber was higher for the 7-day sample. The phytochemical constituents (tannins, saponins, phenols, alkaloids, flavonoids, phytates, oxalates, terpenoids, steroids, and glycosides) were higher for the 3-day than the 7-day sample. The Gas Chromatography-Mass spectrometry technique showed peaks that were characterized as 17 and 20 constituents on days 3 and 7 of the sample, respectively. The antioxidant capacity (ranging from 35.50% to 82.69% for the 3-day and from 37.50% to 84.99% for the 7-day sample) varies by the increasing concentration (7.81 mg/mL to 1000 mg/mL) of the sample. The diameter of zones of inhibition tested at different concentrations (25 mg/mL, 50 mg/mL, and 100 mg/mL) showed varying degrees of activity against Proteus vulgaris and Staphylococcus aureus. The zones obtained were higher 8-10 mg/mL against Staphylococcus aureus and 10-12 mg/mL against Proteus vulgaris for the 7-day fermented sample while 8.0 to 9.0 mg/mL was obtained for the 3-day fermented against Staphylococcus aureus and 8.0 to 10.0 mg/mL against Proteus vulgaris. Overall, the results of this study indicated that fermentation contributed to enhancing the bioactive components and antioxidant capacity of the fermented seeds of N. sativa thereby supporting the use of fermentation in the production of value-added functional foods.
Mediterranean journal of pharmacy and pharmaceutical sciences
Bhaishajya kalpana is an art and science of preparing and dispencing medicine. Guggulu is a Niryasa (oily latex) achieved from small tree called Indian bedellium. Botanical name is commiphora mukul. Guggulu is an amorphous, translucent, solid adhesive, oleo-gum resin is produced by the process of gummosis from its plant. Many other Ayurvedic classics have mentioned various formulations of Guggulu for the treatment of various ailments. Bhashajya ratnawali followed various kalpana use for formuations. Guggulu kalpana is secondary formulations of bhaishajya kalpana. . Guggulu is one among the best binding agents and its used as single or compound drug in the form of pills, Formulations which contains Guggulu as main ingredient, they can be called as Guggulu kalpana. Here in Bhaishajya Ratnawali, Guggulu is used in yoga for both purposes, as a base and as well as medicament also.In bhaishajya Ratnavali Guggulu when modified into different formulations. It can also be used in many diseases along with different combinations of drugs with their anupana, Guggulu kalpana beneficial in treating many diseases. The Guggulu Kalpana is indicated in almost all the strotovikaras and also a number of research works have been proved the wide range of action of Guggulu .
Mahatma Gandhi National Rural Employment Guarantee Act (MGNREGA), with a mandate to provide at least hundred days of guaranteed wage employment in a financial year to every rural household whose members above the age of eighteen years volunteer to do unskilled manual work. The main focus of the act is to facilitate the social protection for the people living in rural India by providing employment opportunities and therefore contributing towards the overall development of the local people. The present study was attempted to figure out the impact of MGNREGA on overall economic and social development of beneficiaries in Gobichettipalayam, Erode district of Tamilnadu.. The results found the MGNREGA has significantly improved their social and economic well-being. The study also has highlighted on the fact that agricultural wages have gone up after the introduction on MGNREGA scheme in the current area.
This proposed work is used to optimize the costs of exceptional elements of machine cells for a variety of components in changing environments to have reduced material movements in cell layout. The exceptional ele¬ments are eliminated in the optimization model by doing machine duplication and part subcontract. Then the shop floor layout is designed to have optimized material movements between cells and within a cell. The result of a linear programming optimization model is cost savings, machines duplicated, parts subcon¬tracted, inter intracellular movements. Finally, the output of the inbound facility design is the floor layout which has machine cell clusters with optimized floor areas. The optimization model is provided with budg¬etary constraints for duplication and the economic tradeoff between machine duplication and part subcontract. Cell layout is prepared to reveal the saving in floor area and material movement lengths than in process layout with the help of distance matrix and dimensions of cells.
Vaccination hesitation may affect the national efforts to slow down the spread of coronavirus among the population. This study was aimed to explore the views of final year pharmacy students at Faculty of Pharmacy, Elmergib University, Al kums, Libya towards COVID-19 vaccination. The study was conducted before the vaccine becomes available in Libya. A semi-structured questionnaire was distributed on March 14, 2021 to the fourth- year pharmacy students at Elmergib University, Al khums Libya. Results showed a high degree of hesitancy towards vaccination against this virus (52.6%). Student's participants who said they would take the vaccine probably have said that because of their stress that caused by COVID-19 pandemic (47.4%). With regard to the gender, the participants’ views had no significant difference between male and female students on whether to take the vaccine or not (P = 0.825). In conclusion, hesitations towards vaccination and stress caused by student fear from the virus need to be addressed to minimize public reluctant to take the vaccine and to improve the education process during the pandemic.
Mediterranean journal of pharmacy and pharmaceutical sciences
Herbal products are being paid particular attention by people around the world since they are natural, effective, and without side effects. In modern medicine, some drugs prescribed to the patients are derived from medicinal plants. Thus, the aim of this study is to investigate the central nervous effects of methanol extract of Ephedra altissima stems, in Albino mice. Doses of 500, 1500, and 3000 mg/kg of the methanol extract were administered in sub-acute doses (three doses), intraperitoneally at 24, 5.0, and 1.0 hours before scoring. General locomotor behavior profile, antidepressant activity, and anxiolytic activity were studied. The results revealed that the methanol extract of Ephedra altissima at 500, 1500, and 3000 mg/kg produced central nervous system depression, a remarkable decrease in the immobility time (forced swimming maze test), no anxiolytic-like effect by using elevated plus-maze model of anxiety. These results suggest that methanol extract of Ephedra altissima exhibits a central depressant activity, antidepressant-like activity, and mild antipsychotic activity without anxiolytic-like effect in tested experimental animal models with the doses used. Therefore, it can be concluded that Ephedra altissima extract may have a central depression, antidepressant-like activity with no effect as anxiolytic-like mood.
Mediterranean journal of pharmacy and pharmaceutical sciences
On 18 March 2020, all South African universities and colleges were closed due to the COVID-19 virus. By early April, 10 universities announced that they were planning to resume teaching and learning online, including the University of the Witwatersrand (i.e., Wits University), Johannesburg, which is the joint highest ranked university in Africa. Therefore, the purpose of this editorial was to examine the perceptions and attitudes of these students regarding online learning in an era of disruption of COVID-19, uniquely using both multi-mixed methods research approaches (i.e., involving the partial integration of multiple methods research approaches and mixed methods research approaches) and meta-methods study approaches (i.e., involving the full[er] integration of multiple methods research approaches and mixed methods research approaches). A total of 4,419 Wits University students completed an online survey. A principal components analysis of one of survey’s scales, namely, the Attitude of Students Towards COVID-19 and its Impact on Higher Education scale, revealed 2 subscales, namely, Students’ Self-regulation Towards COVID-19-Based Higher Education and Attitudes Toward Teaching, Learning, and Assessment in COVID-19-Based Higher Education. Nonparametric analyses revealed that scores on these measures discriminated gender, age group, level of student (i.e., undergraduate vs. postgraduate), locality status (i.e., local vs. international student), and registration status (i.e., full-time vs. part-time). A multiple analysis of the open-ended responses by the VOSviewer 1.6.14 text mining software program led to the identification of 6 metathemes. Similarly, WordStat 8.0.29 topic modeling yielded 5 metathemes that mapped onto VOSviewer’s 6 metathemes, indicating triangulation of findings. A sentiment analysis revealed negative sentiments that identified not only the biggest challenges for students but also the characteristics of students who experience these challenges. Finally, a cluster analysis, combined with chi-square analyses, led to the identification of 4 clusters of students who differed with respect to their attitudes and online experiences. Implications of these findings are discussed.
Foreign bodies (FBs) in the scalp are a common incident following head trauma, especially in traffic accidents, and are detected in the early post-traumatic period. The persistence of these FBs may cause pain and paresthesia. We report a case of 41 years old man, whose victim it’s been 20 years of physical aggression, in which the victim was hit by a brick occasioning a frontal wound stitched at the time without sufficient exploration. Months later, the patient presented several episodes of a frontal scalp nodular lesion with pus leakage (Fig. 1). The lesions were only treated with local antibacterial agents. Four years before the patient consults at our level, he consulted a dermatologist who performed a removal of the skin lesion. Months later, the lesion reappeared. At our level the clinical examination suspected a bone lesion, so CT was performed. Brain imaging was strongly evoking bone tumors or osteitis (Fig. 2). The patient was operated on under general anesthesia. First, a carcinogenic removal of the scalp lesion was performed; then, when reaching the bone, hard red friable bodies well separated from proportionally healthy bone were found. Those findings raise suspicion of the presence of FBs nested in the bone from the first head trauma. Hence, a carcinologic removal of the affected bone was postponed, and simple curettage was performed (Fig. 3). The post-operative course was without complications. The histological study confirmed per-operative findings: Multiple stony FBs associated with inflammatory reaction especially lymphocytes around vessels and the FBs.
Mushrooms and fenugreek are widely used to reduce hyperglycemia, and fenugreek is also used as a culinary ingredient to enhance flavor and aroma. This study is aimed at investigating the underlying mechanisms of the hypoglycemic effects of mushrooms and fenugreek in a Type 2 diabetic rat model. Adenosine monophosphate (AMP)–activated protein kinase (AMPK) functions to reduce hyperglycemia through insulin-independent pathways and protects beta-cells. Diabetic model rats were administered standard diets supplemented with 5% oyster mushroom powder (mushroom-treated (MT) group) and 5% fenugreek seed powder (fenugreektreated (FT) group) for 8 weeks. The results showed improvements in both glycemic and lipid profiles, with both oyster mushroom and fenugreek enhancing the phosphorylation of AMPK in muscle tissue. However, no effect on insulin secretion was observed. These findings suggest that both substances reduce hyperglycemia through an insulin-independent pathway. In silico analysis of both mushroom and fenugreek seed extracts revealed bioactive compounds having a strong binding affinity to α-glucosidase, which suggests mushroom and fenugreek supplements might control postprandial blood glucose levels.
Recently, wireless sensor networks (WSNs) have been deployed for a wide variety of applications, including military sensing and tracking, patient status monitoring, traffic flow monitoring, where sensory devices often move between different locations. Securing data and communications requires suitable encryption key protocols. In this paper, we propose a certificateless-effective key management (CL-EKM) protocol for secure communication in dynamic WSNs characterized by node mobility. The CL-EKM supports efficient key updates when a node leaves or joins a cluster and ensures forward and backward key secrecy. The protocol also supports efficient key revocation for compromised nodes and minimizes the impact of a node compromise on the security of other communication links. A security analysis of our scheme shows that our protocol is effective in defending against various attacks.We implement CL-EKM in Contiki OS and simulate it using Cooja simulator to assess its time, energy, communication, and memory performance.
This study sets out to explore the Critical Success Factors (CSFs) necessary for Total Quality Management (TQM) implementation in hotels. It also aims to classify participating hotels into groups based on their TQM adoption by using cluster analysis. A quantitative survey method was applied. Data were collected from a sample of managers from four- and five-star hotels in Jordan, 170 questionnaires were distributed to managers and 104 usable questionnaires were returned. The findings revealed that TQM is existed and implemented in the hotel industry. The researcher then confirmed that four- and five-star hotels can be classified into two groups, namely, “high TQM adopters” and “low TQM adopters”.
The aim of this work was to prepare chitosan nanoparticles loaded with antineoplastic drug Lomustine (LCNPs), by ionic-gelation method with homogenization. The nanoparticles were characterized for particle size, polydispersity index (PDI), surface morphology, encapsulation efficiency, in-vitro drug release and cytotoxicity on human lung cancer cell line L132 by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The particle size, zeta potential and encapsulation efficiency of prepared nanoparticles ranged from 75±1.1 to 637±1.6 nm (PDI from 0.05±0.001 to 0.18±0.007), 37.2±0.21 to 53.8±0.18 mV and 66.74±1.4 to 98.0±1.8% re- spectively. The particles were spherical in shape with smooth surface in scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images. Mechanical shearing by homogenization treatment significantly changed the nanoparticle size. The drug release rate was biphasic and diffusion controlled over the 8 h. LCNPs greatly inhibited the growth of the L132 cancer cell line used in this study in comparison to the native Lomustine (LMT).
India’s economic system has undergone significant changes in recent years reflecting globalization and changes in national policies. This paper provides a comprehensive analysis of India’s economic growth, focusing on imports and exports. The study explores the key drivers of economic expansion, including trade liberalization, trade agreements, and technological advancement. It also explores the impact of international trade and geopolitical events on business models. It assesses the role of policy measures such as the Goods and Services Tax (GST), the Make in India initiative, and various free trade agreements in generating economic benefits. The paper also assesses the trade balance and its impact on India’s economic stability and growth. The paper concludes with recommendations for improving the market, including diversifying entrepreneurs, investing in infrastructure, and strengthening the domestic economy. The review provides insights to policymakers, businesses, and academics who want to understand and harness India’s economic potential in the global economy.
Université Nazi Boni
Central Council For Research In Unani Medicine, Ministry Of Ayush, Government Of India, New Delhi